2-(2-Methylphenyl)ethanol
Supplier:
MP Biomedicals
Description:
Oligomycin is a natural antibiotic isolated from Streptomyces diastatochromogenes, which is a mixture of oligomycins A, B, and C.
Supplier:
Adipogen
Description:
KU0063794 is a highly specific inhibitor of the mammalian target of rapamycin (mTOR). It inhibits both mTORC1 and mTORC2 with an IC(50) of approximately 10nM.
Supplier:
Adipogen
Description:
Selective inhibitor of COX−1. Resveratrol is a phenolic phytoalexin found in grape skin and other plants. It has intracellular antioxidant activity and activates SIRT1, a NAD+-dependent histone deacetylase involved in mitochondrial biogenesis and the enhancement of peroxisome proliferator-gamma-activated receptor coactivator-1alpha (PGC-1alpha) and FOXO activity. The anti-diabetic, neuroprotective and anti-adipogenic actions of resveratrol may be mediated via SIRT1 activation.
Catalog Number:
(103529-156)
Supplier:
New England Biolabs (NEB)
Description:
Need more RNA Wash Buffer? No problem. Monarch® kit components are all available for purchase separately.
Supplier:
MilliporeSigma
Description:
A tripeptide that serves as a component of the [gamma]-glutamyl amino acid transport system. An endogenous antioxidant that provides protection against auto-oxidation.
Catalog Number:
(80054-800)
Supplier:
MilliporeSigma
Description:
A potent and reversible inhibitor of histone deacetylase
Supplier:
Adipogen
Description:
Antibiotic
Catalog Number:
(10282-038)
Supplier:
Bioss
Description:
The alcohol dehydrogenase family of proteins metabolize a wide variety of substrates, including retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. ADH5 (alcohol dehydrogenase 5 (class III)), also known as FDH (formaldehyde dehydrogenase), ADHX, ADH-3 or GSNOR, is a 374 amino acid cytoplasmic protein that belongs to the class III subfamily of alcohol dehydrogenases. Expressed ubiquitously, ADH5 uses iron as a cofactor to catalytically oxidize both long-chain primary alcohols and S-hydroxymethyl-glutathione, a product formed spontaneously between formaldehyde and glutathione. ADH5 exists as a homodimer and, via its ability to oxidize S-hydroxymethyl-glutathione and, thus, eliminate formaldehyde, functions as an important component of cellular metabolism. Genetic variations in the gene encoding ADH5 may affect drug and alcohol dependence in humans.
Catalog Number:
(10282-040)
Supplier:
Bioss
Description:
The alcohol dehydrogenase family of proteins metabolize a wide variety of substrates, including retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. ADH5 (alcohol dehydrogenase 5 (class III)), also known as FDH (formaldehyde dehydrogenase), ADHX, ADH-3 or GSNOR, is a 374 amino acid cytoplasmic protein that belongs to the class III subfamily of alcohol dehydrogenases. Expressed ubiquitously, ADH5 uses iron as a cofactor to catalytically oxidize both long-chain primary alcohols and S-hydroxymethyl-glutathione, a product formed spontaneously between formaldehyde and glutathione. ADH5 exists as a homodimer and, via its ability to oxidize S-hydroxymethyl-glutathione and, thus, eliminate formaldehyde, functions as an important component of cellular metabolism. Genetic variations in the gene encoding ADH5 may affect drug and alcohol dependence in humans.
Supplier:
Adipogen
Description:
Induces neuritogenesis. Potent and selective irreversible proteasome inhibitor. Specifically inhibits 20S proteasome (MCP; multicatalytic complex). Blocks proteasome activity by targeting the catalytic beta-subunit. Apoptosis inducer. Anticancer compound. Upregulates HSP70 and HSP22. Induces differentiation and inhibits cell cycle progression in several tumor cell lines. Inhibits NF-kappaB activation by inhibiting IkappaB degradation. Cathepsin A inhibitor. beta-Secretase activity inhibitor. Anti-adipogenic. Autophagy inducer.
Catalog Number:
(80057-972)
Supplier:
MilliporeSigma
Description:
A cell-permeable and irreversible antitumor and anti-inflammatory agent that acts as an inhibitor of 5-lipoxygenase (IC₅₀ = 8 µM) and cyclooxygenase (IC₅₀ = 52 µM).
Supplier:
Adipogen
Description:
Potent and selective inhibitor of cyclin dependent kinases CDK1, CDK2, CDK5 and CDK9. Apoptosis inducer. Inhibits the proliferation of various cancer cell lines. Casein kinase 1 (CK1delta/epsilon) and DYRK1A inhibitor. Potential anti-inflammatory compound. Potential antidiabetic compound.
Supplier:
Adipogen
Description:
Cabozantinib is very potent inhibitor, with an IC(50) of less than 10nM for VEGFR2, MET, Kit and FLT3-ITD.
Supplier:
TCI America
Description:
CAS Number: 1611-35-4
MDL Number: MFCD00014580 Molecular Formula: C31H32N2O13S Molecular Weight: 716.62 Form: Crystal Color: Yellow Red
Catalog Number:
(IC15375125)
Supplier:
MP Biomedicals
Description:
Tricyclic antidepressant; inhibits serotonin and norepinephrine transporters.
Supplier:
Electron Microscopy Sciences
Description:
A water soluble embedding media which is based on Glycol Methacrylate (GMA) plastic embedding. It is intended for use in preparing samples for high resolution microscopes (HRLM). The catalyzed monomer acts as a dehydration and infiltration agent. Therefore, complete dehydration through 100% ethanol is not necessary although recommended for large or dense tissues. Conventional paraffin sections have a greater degree of shrinkage and produce inadequate morphology when compared to JB-4.JB-4 Kit Consists of 800 mL Solution A, 30 mL Solution B, and 12 g Catalyst.
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