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2-(Benzyloxy)-3,5-dimethylbenzoic+acid
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2-(Benzyloxy)-3,5-dimethylbenzoic+acid
Catalog Number:
(10749-390)
Supplier:
Prosci
Description:
FAIM2 Antibody: Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. FAIM2 is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-alpha death signal. In this respect, FAIM2 is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. FAIM2, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. FAIM2 is widely distributed, but highly expressed in the hippocampus and other neural tissues. FAIM2 was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.
Supplier:
RPI
Description:
The highest purity D-Luciferin Potassium Salt for a wide range of bioluminescent applications. Produces bioluminescence when oxidized by firefly luciferase. Allows highly sensitive bioluminescent measurements. Common research uses reporter gene assays, ATP assays, whole animal studies, DNA sequencing and others. Our product is specially purified and tested extensively to ensure the highest signal and reproducibility with low background and sensitivity. Guaranteed purity is determined by both standard HPLC and Chiral HPLC methods. Protect from light and moisture.
Supplier:
TCI America
Description:
CAS Number: 57671-28-0
MDL Number: MFCD06797154 Molecular Formula: C17H28O6 Molecular Weight: 328.41 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Color: Very Pale Yellow Specific Gravity (20/20): 1.10
Catalog Number:
(100273-008)
Supplier:
Indofine Chemical Company
Description:
Rare Organics & BioChemicals 16966-07-7 5gm Z-Thr(tBu)-OH. DCHA salt 490.7 Room temperature.
Catalog Number:
(89415-418)
Supplier:
Prosci
Description:
LFG Antibody: Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. LFG is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-alpha death signal. In this respect, LFG is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. LFG, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. LFG is widely distributed, but highly expressed in the hippocampus and other neural tissues. LFG was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.
Catalog Number:
(103634-094)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the human IL27B (NP_005746.2)(Met1-Lys229) was fused with a flag tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the human IL12A (P29459-1)(Met1-Ser219) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids were co-expressed and the human IL27B and IL12A heterodimer was purified.
Supplier:
AMBEED, INC
Description:
4'-Benzyloxyacetophenone 98%
Catalog Number:
(10072-946)
Supplier:
Prosci
Description:
Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-3 regulates a number of biological processes, including embryogenesis, inflammatory responses, cell progression and metastasis. Galectin-3 is normally expressed in epithelia of a variety of tissues, including colon and endometrium, and in various inflammatory cells, including macrophages. Galectin-3 can function intracellularly, in controlling cell cycle and preventing T-cell apoptosis, and also extracellularly, in activating various cells, including monocytes/macrophages, mast cells, neutrophils, and lymphocytes. Expression of Galectin-3 is affected by neoplastic transformation, being up-regulated in certain types of lymphomas, and in thyroid and hepatic carcinomas. Conversely, it is down-regulated in other cancers, such as colon, breast, ovarian, and uterine. Recombinant human Galectin-3 is a globular 26.0kDa protein containing 250 amino acid residues, but no disulfide bonds.
Catalog Number:
(103280-104)
Supplier:
Novus Biologicals
Description:
The Annexin A3 Antibody from Novus Biologicals is a rabbit polyclonal antibody to Annexin A3. This antibody reacts with human, mouse, rat. The Annexin A3 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Catalog Number:
(TCC2334-5G)
Supplier:
TCI America
Description:
CAS Number: 3496-11-5
MDL Number: MFCD00053547 Molecular Formula: C17H20N2O6 Molecular Weight: 348.36 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 116 Specific rotation [a]20/D: -24 deg (C=1, Dioxane) Storage Temperature: <0°C
Supplier:
TCI America
Description:
CAS Number: 1676-81-9
MDL Number: MFCD00077039 Molecular Formula: C12H15NO5 Molecular Weight: 253.25 Purity/Analysis Method: >98.0% (N) Form: Crystal Melting point (°C): 37 Flash Point (°C): 113 Specific rotation [a]20/D: -15 deg (C=1, MeOH) Storage Temperature: 0-10°C
Supplier:
PeproTech, Inc.
Description:
Sclerostin, a glycoprotein predominantly secreted by osteocytes, is a member of the Cerberus/DAN family of putative BMP antagonists that functions as an endogenous regulator of the canonical Wnt signaling pathway and an inhibitory regulator of bone homeostasis. Although expressed nearly exclusively by osteocytes, sclerostin can also be found at significant levels elsewhere, such as bone, bone marrow, cartilage, the kidney, and the liver, and has also been shown to be produced by hypertrophic chondrocytes and cementocytes. Like DKK family members DKK-1 and DKK-4, sclerostin plays an important regulatory role in the Wnt/beta-catenin signaling pathway by forming inhibitory complexes with LDL Receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/beta-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/beta-catenin signaling cascade. Sclerostin has also been shown to interact directly with LRP4 via its extracellular domain to facilitate inhibition of Wnt signaling, and can catabolically promote osteoclast activity by increasing osteocyte expression of RANKL. Sclerostin's critical involvement in the regulation of bone formation and resorption is emphasized by two bone dysplasia disorders, sclerosteosis and van Buchem disease (VBD), caused by rare autosomal recessive mutations that result in progressive bone overgrowth and hypermineralization due to markedly decreased sclerostin levels. PeproTech's CHO cell-derived Recombinant Human Sclerostin is a 190-amino-acid-length glycoprotein with a calculated molecular weight of 21.5 kDa. As a result of glycosylation, Recombinant Human Sclerostin migrates with an apparent molecular mass of approximately 28-35 kDa by SDS-PAGE gel, under non-reducing conditions.
Supplier:
Matrix Scientific
Description:
4-Benzyloxyindole ≥99%
Catalog Number:
(76011-686)
Supplier:
Prosci
Description:
HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
Catalog Number:
(101808-994)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 019892-500MG , MDL Number: MFCD03422407
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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