Supplier:
Thermo Scientific Chemicals
Description:
1g CAS: 481681-02-1, MDL: MFCD08235075
Catalog Number:
(10266-442)
Supplier:
Bioss
Description:
Sulfatases are enzymes that hydrolyse a diverse range of sulfate esters. Deficiency of lysosomal sulfatases leads to human diseases characterized by the accumulation of either GAGs (glycosaminoglycans) or sulfolipids. Sulfamidase, also known as HSS, SFMD, MPS3A or SGSH, is a 502 amino acid lysosome that belongs to the sulfatase family. It has been suggested that sulfamidase may be involved in the lysosomal degradation of heparan sulfate. Defects in the gene encoding sulfamidase are the cause of Sanfilippo syndrome A, an autosomal recessive lysosomal storage disease caused by impaired degradation of heparan sulfate. Sanfilippo syndrome A is characterized by severe central nervous system degeneration but relatively mild somatic manifestations.
Supplier:
ALADDIN SCIENTIFIC
Description:
Azido-PEG4-C2-carboxylic acid ≥97%
Supplier:
AOB CHEM USA
Description:
(3-Ethoxy-2,4-difluoro-5-formylphenyl)boronic acid ≥97%
Supplier:
AOB CHEM USA
Description:
2-Methoxy-4-(trifluoromethoxy)benzeneboronic acid ≥97%
Catalog Number:
(10293-358)
Supplier:
Bioss
Description:
FDPS is a 419 amino acid enzyme belonging to the FPP/GGPP synthetase family. Localized to cytoplasm and peroxisome, FDPS expression is regulated by phorbol esters and polyunsaturated fatty acids. FDPS assists in cholesterol biosynthesis, post-translational protein modifications and synthesis of steroid hormones in the isoprenoid pathway.FDPS catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FDPS is inactivated by interferon-induced RSAD2, which may result in the disruption of lipid rafts at the plasma membrane. Existing as a homodimer, FDPS may have anti-viral effects when inactivated by RSAD2. Reduced activity of FDPS in liver may partly be the cause of Zellweger syndrome and neonatal adrenoleukodystrophy, both of which are known to be peroxisomal deficiency diseases.
Catalog Number:
(10293-350)
Supplier:
Bioss
Description:
FDPS is a 419 amino acid enzyme belonging to the FPP/GGPP synthetase family. Localized to cytoplasm and peroxisome, FDPS expression is regulated by phorbol esters and polyunsaturated fatty acids. FDPS assists in cholesterol biosynthesis, post-translational protein modifications and synthesis of steroid hormones in the isoprenoid pathway.FDPS catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FDPS is inactivated by interferon-induced RSAD2, which may result in the disruption of lipid rafts at the plasma membrane. Existing as a homodimer, FDPS may have anti-viral effects when inactivated by RSAD2. Reduced activity of FDPS in liver may partly be the cause of Zellweger syndrome and neonatal adrenoleukodystrophy, both of which are known to be peroxisomal deficiency diseases.
Supplier:
AMBEED, INC
Description:
4-[2-(Ethoxycarbonyl)ethyl]benzeneboronic acid 98%
Supplier:
AMBEED, INC
Description:
(3-(Naphthalen-2-yl)phenyl)boronic acid, Purity: 98%, CAS number: 870774-29-1, Appearance: Form: Crystal - Powder / Colour: White - Very pale yellow, Storage: Inert atmosphere, 2-8C, Size: 1G
Supplier:
ALADDIN SCIENTIFIC
Description:
2-Aminoacetamidine dihydrobromide may be used in the synthesis of 2-amino-5-(4-(2-(N-benzyloxycarbonylamino)ethoxy)phenyl)pyradine.
Supplier:
AOB CHEM USA
Description:
(3-Ethoxy-2-fluoro-6-(methylthio)phenyl)boronic acid ≥97%
Catalog Number:
(10266-450)
Supplier:
Bioss
Description:
Sulfatases are enzymes that hydrolyse a diverse range of sulfate esters. Deficiency of lysosomal sulfatases leads to human diseases characterized by the accumulation of either GAGs (glycosaminoglycans) or sulfolipids. Sulfamidase, also known as HSS, SFMD, MPS3A or SGSH, is a 502 amino acid lysosome that belongs to the sulfatase family. It has been suggested that sulfamidase may be involved in the lysosomal degradation of heparan sulfate. Defects in the gene encoding sulfamidase are the cause of Sanfilippo syndrome A, an autosomal recessive lysosomal storage disease caused by impaired degradation of heparan sulfate. Sanfilippo syndrome A is characterized by severe central nervous system degeneration but relatively mild somatic manifestations.
Catalog Number:
(TS44141-0050)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
PyOxim 97%
Supplier:
AMBEED, INC
Description:
(E)-(2-(3-Ethoxy-3-oxoprop-1-en-1-yl)phenyl)boronic acid, Purity: 95%, CAS Number: 2828439-78-5, Appearance: Solid, Storage: Inert atmosphere, 2-8C, Size: 1G
Supplier:
Matrix Scientific
Description:
MF=C16H24N2O3 MW=292.38 CAS=138227-63-1 MDL=MFCD04115023 1G
Supplier:
AMBEED, INC
Description:
(3-Chloro-2-fluoro-5-(trifluoromethyl)phenyl)boronic acid 97%
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