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4-Isopropylbenzylamine
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4-Isopropylbenzylamine
Supplier:
AMBEED, INC
Description:
GDC-0623 99+%
Catalog Number:
(AAH33811-06)
Supplier:
Thermo Scientific Chemicals
Description:
5g CAS: 884495-03-8, MDL: MFCD05662413
Supplier:
AMBEED, INC
Description:
cis-N-((S)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethyl)-1-methoxy-4-(4-methyl-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)cyclohexanecarboxamide, Purity: 99%, CAS Number: 2097132-94-8, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, Store in freezer, under -20C, Size: 25MG
Supplier:
AMBEED, INC
Description:
4-(N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-(trifluoromethoxy)benzyl)sulfamoyl)benzoic acid, Purity: 98+%, CAS Number: 1254205-52-1, Appearance: Form: solid, Storage: Inert atmosphere, 2-8 C, Size: 10mg
Catalog Number:
(77625-682)
Supplier:
AMBEED, INC
Description:
Ifebemtinib 98%
Supplier:
AMBEED, INC
Description:
6-(((1R,2S)-2-aminocyclohexyl)amino)-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one hydrochloride, Purity: 98+%, CAS Number: 1952251-28-3, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 10mg
Supplier:
Adipogen
Description:
PF-562,271 is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 catalytic activity with a IC(50) of 1.5 and 14nM, respectively. In addition, PF-562,271 displayed robust inhibition in an inducible cell-based assay measuring phospho-FAK with an IC(50) of 5nM. PF-562,271 was evaluated against multiple kinases and displays <gt/>100x selectivity against a long list of nontarget kinases. In tests, PF-562,271 inhibits FAK phosphorylation in vivo in a dose-dependent fashion with a calculated EC50 of 93ng/mL using injections.
Supplier:
ALADDIN SCIENTIFIC
Description:
2-Amino-3-bromo-5-methylpyridine may be used in the synthesis of: . 3-bromo-2-chloro-5-methylpyridine . 3-bromo-2-fluoro-5-methylpyridine . 8-methyl-1,2,3,5-tetrahydropyrido[3,4-b][1,4]diazepin-4-one . 3-bromo-2-(ethylamino)-5-methylpyridine . (3-bromo-5-methylpyridin-2-yl)aniline . 5-methyl-3-(phenylethynyl)pyridin-2-amine . 3-[(2-methoxyphenyl)ethynyl]-5-methylpyridin-2-amine . 3-[(4-methoxyphenyl)ethynyl]-5-methylpyridin-2-amine . 3-[(3-chlorophenyl)ethynyl]-5-methylpyridin-2-amine
Supplier:
Adipogen
Description:
AG13958 is a VEGF inhibitor that was in clinical development for treatment of age-related macular degeneration (AMD). The drug displays low water solubility and so far in trials delivery has been difficult needing direct injection to be truly effective and it varied by the species used because of species specific differences in eye circulation and vascularization. As a VEGF inhibitor AG13958 was targeted to FLT/TYK receptor inhibition.
Supplier:
AMBEED, INC
Description:
RO5126766 ≥98%
Supplier:
Adipogen
Description:
Nilotinib is an orally bio-available aminopyrimidine-derivative Bcr-Abl tyrosine kinase inhibitor (IC(50) <lt/>30nM) with anti-neoplastic activity.
Supplier:
Adipogen
Description:
Inhibitor of pan-Trk activity (IC(50) = 8 and 12nM for TrkA and TrkB). Shown to target Trk (tropomyosin receptor kinase) ATP binding cleft and an immediately adjacent hydrophobic pocket. Preferentially arrests the proliferation of Ba/F3 cells fused with Tel-TrkA, Tel-TrkB and Tel-TrkC (IC(50) = 11, 9 and 7nM, respectively) and in Ba/F3 and RIE cells expressing both TrkA and NGF (IC(50) = 42 and 17nM, respectively) over Mo7e-c-Kit and Rat-A10-PDGFR (IC(50) = 1 and 0.5µM) and Ba/F3-Tel-KDR and wt-Ba/F3 cells (IC(50) = 3.0 and 5.6µM). Displays ~100-fold greater selectivity among a panel of 59 closely related kinases and in 33 cellular kinase assays. Weakly active against relevant cytochrome P450 isozymes and hERG channel, and exhibit adequate microsomal stability, pharmacokinetic profile and efficacy in mice and rats. Suppresses tumor growth in a mouse RIE-TrkAmNGF xenograft model (50mg/kg, p.o.).
Supplier:
ALADDIN SCIENTIFIC
Description:
2-Amino-3,5-dichloropyridine was used in the synthesis of bis(2-amino-3,5-dihalopyridinium) tetrahalocuprate(II) compounds and 2-fluoro-3,5-dichloropyridine.
Catalog Number:
(AAAL19554-03)
Supplier:
AMBEED, INC
Description:
2-Bromo-6-(trifluoromethyl)pyridine 98%
Supplier:
APOLLO SCIENTIFIC
Description:
2-(Trifluoromethyl)pyridine
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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