1-(2-Aminophenyl)piperazine
Supplier:
AOB CHEM USA
Description:
4-[Methoxy(methyl)carbamoyl]benzeneboronic acid ≥97%
Supplier:
ALADDIN SCIENTIFIC
Description:
ADL5859 is a δ-opioid receptor agonist with Ki of 0.8 nM, selectivity against opioid receptor κ, μ, and weak inhibitory activity at the hERG channel.A selective receptor agonist for the δ-opioid receptor
Supplier:
ALADDIN SCIENTIFIC
Description:
Axitinib is a non-selective receptor kinase inhibitor of Flt and Flk proteins. This compound also inhibits Flt-1(VEGFR-1), Flk-1(VEGFR-2), Flt-4(VEGFR-3), PDGFR-β and c-Kit(c-KIT) with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM, respectively. Axitinib is studied as an antitumor agent of various cell lines. Axitinib is an inhibitor of PDGFR-β.An inhibitor of Flt and Flk (VEGFR) with antitumor properties
Application: Axitinib has been used as a vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitor (TKI) to study its effect on renal cancer cell proliferation in vitro. It has also been used to inhibit anterior mesenteric artery (AMA) angiogenesis in dechlorinated embryos maintained in conditioned water (CW).
Supplier:
TCI America
Description:
CAS Number: 67219-55-0
MDL Number: MFCD00010114 Molecular Formula: C37H35N3O7 Molecular Weight: 633.70 Purity/Analysis Method: >99.0% (HPLC) Form: Crystal Melting point (°C): 119 Specific rotation [a]20/D: 58 deg (C=1, MeOH)
Supplier:
Adipogen
Description:
CYT387 is selective inhibitor of JAK1 and JAK2 kinases including the JAK2V617F mutant . Using ATP kinase assays IC(50) values for JAK1 (11nm), JAK2, (18nM), JAK2, JAK2V617F (23nM) JAK3 (155nM), and TYK2 (17nM). In testing kinase arrays, CYT387 also had activity (defined as an IC(50) <lt/> 100nM) detected against CDK2/cyclin A, MAPK8 (JNK1), PRKCN (PKD3), PRKD1 (PKCµ), ROCK2, and TBK1 kinase as well.
Supplier:
AMBEED, INC
Description:
N6-Benzoyl-2',3'-isopropylidene adenosine 97%
Supplier:
AMBEED, INC
Description:
4-Carbamoylphenylboronic acid pinacol ester 95%
Catalog Number:
(101935-066)
Supplier:
Matrix Scientific
Description:
MF=C11H15N3O MW=205.26 250Mg
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
N-α-Benzoyl-DL-arginine-4-nitroanilide hydrochloride 98%
Catalog Number:
(BT220760-10G)
Supplier:
BeanTown Chemical
Description:
CAS: 26661-13-2; MDL No: MFCD00239434
Powder; Molecular Formula: C11H9N3O2; MW: 215.21
Melting Point: <gt/>300° (decomposes)
Catalog Number:
(TCC0578-025G)
Supplier:
TCI America
Description:
CAS Number: 25395-22-6
MDL Number: MFCD00025472 Molecular Formula: C9H9NO4 Molecular Weight: 195.17 Purity/Analysis Method: >99.0% (T) Form: Crystal Melting point (°C): 222
Catalog Number:
(76719-332)
Supplier:
AMBEED, INC
Description:
N-α-Benzoyl-L-arginine 4-nitroanilide hydrochloride 97%
Catalog Number:
(82603-346)
Supplier:
MilliporeSigma
Description:
PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A cell-permeable benzoylthiourea compound that activates p53 and displays antitumor properties. Acts as a reversible and noncompetitive inhibitor of sirtuins1,2 (IC50 ~ 10 ¦M for SIRT2) with selectivity over HDACs. Shown to protect p53 from MDM2-mediated degradation, induce cell death, and delay tumor growth in several cell lines and in xenograft mouse model (92 mg/kg, i.p.). Purity: ?98% by HPLC. Ref.: Lain, S., et al. 2008. Cancer Cell 13, 454.
Catalog Number:
(BT144860-1G)
Supplier:
BeanTown Chemical
Description:
CAS: 57227-09-5
Solid; Molecular Formula: C22H28N2O3; MW: 368.47
Supplier:
Bachem Americas
Description:
Sequence: Bz-Arg-pNA · HCl
Supplier:
TCI America
Description:
CAS Number: 655-42-5
MDL Number: MFCD00070521 Molecular Formula: C13H17NO6 Molecular Weight: 283.28 Purity/Analysis Method: >98.0% (N) Form: Crystal Specific rotation [a]20/D: 43 deg (C=2, H2O)
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