2-Chloro-5-methoxybenzyl+alcohol
Supplier:
Matrix Scientific
Description:
MF=C14H11CLIN3O MW=399.62 CAS=1246349-97-2 MDL=MFCD19689569 1G
Supplier:
AMBEED, INC
Description:
(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide, Purity: 98%, CAS Number: 330784-47-9, Appearance: White to off-white powder or crystals, Storage: Sealed in dry, Store in freezer, under -20 C, Size: 100mg
Catalog Number:
(77190-452)
Supplier:
AMBEED, INC
Description:
1-(Bromomethyl)-3-chloro-5-methoxybenzene, Purity: 97%, CAS Number: 885270-32-6, Appearance: White to light-yellow powder or crystals, Storage: Inert atmosphere, 2-8 C, Size: 100mg
Supplier:
ALADDIN SCIENTIFIC
Description:
Avanafil is a highly selective PDE5 inhibitor with IC50 of 5.2 nM, >121-fold selectivity over other PDEs.
Supplier:
Bachem Americas
Description:
The Wang support, p-benzyloxybenzyl alcohol resin, is the most widely used resin for attaching carboxylic acids for further functionalization. Cleavage conditions for the ester anchor involve concentrated TFA or TFA/CH₂Cl₂ to provide carboxylic acids or cyclization-cleavage under acidic or basic conditions. Release of an amide function by treatment with an amine in the presence of a Lewis acid was also reported. Wang resin was used to add vinyl and iodobenzoic acids via carbodiimide coupling and the products subjected to Heck conditions with alkenes or with alkynes or to Suzuki coupling with boron reagents. The Ugi multicomponent condensation reaction was conducted on Wang resin with the carboxylic acid, amine or isonitrile as the anchored functional group. Solid-phase lactam syntheses were also achieved by reaction of the resin-bound isonitrile with an amine and an ω-keto-acid as well as other synthetic transformations such as the Biginelli reaction and construction of heterocycles such as quinolones, imidazoles, hydantoins, and 1,4-benzodiazepine-2,5-diones. On a Wang resin primary, secondary, and tertiary alcohols have been converted to 4-methoxybenzyl ethers. As well as anchoring carboxylic acids to Wang resin, phenols were attached under Mitsunobu conditions, subjected to further transformations and cleaved under acidic conditions.
Supplier:
AMBEED, INC
Description:
4-Chloro-2-fluorobenzyl alcohol 98%
Catalog Number:
(77684-511)
Supplier:
AMBEED, INC
Description:
3-Chloro-2-nitrobenzyl alcohol ≥97%, Ambeed.Inc
Supplier:
AMBEED, INC
Description:
2-Chloro-6-fluorobenzyl alcohol 95%
Supplier:
AMBEED, INC
Description:
4-Chloro-3-fluorophenethyl alcohol 95%
Supplier:
AOB CHEM USA
Description:
5-Chloro-2-(methylthio)benzyl alcohol ≥95%
Supplier:
AOB CHEM USA
Description:
4-Chloro-2,3-difluorobenzyl alcohol ≥97%
Supplier:
AOB CHEM USA
Description:
2-Chloro-3-methylbenzyl alcohol ≥97%
Catalog Number:
(77746-822)
Supplier:
AMBEED, INC
Description:
5-Chloro-2-hydroxybenzyl alcohol ≥98%
Supplier:
AOB CHEM USA
Description:
4-Chloro-3,5-difluorobenzyl alcohol ≥97%
Supplier:
AOB CHEM USA
Description:
2-Chloro-5-fluoro-3-methylbenzyl alcohol ≥97%
Supplier:
Thermo Scientific Chemicals
Description:
2-Chloro-5-nitrobenzyl alcohol 98%
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