Catalog Number:
(101833-948)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 032538-1G , MDL Number: MFCD02180819
Supplier:
AMBEED, INC
Description:
4-Chloro-2-(trifluoromethyl)nicotinic acid, Purity: 95%, CAS number: 1018678-39-1, Appearance: Solid, Storage: Inert atmosphere, 2-8C, Size: 1G
Supplier:
TCI America
Description:
1-Methyl-5-(trifluoromethyl)pyrazole-4-carboxylic Acid, Purity: >98.0%(GC)(T), CAS number: 119083-00-0, Molecular Formula: C6H5F3N2O2, Molecular Weight: 194.11, Form: Crystal - Powder, White - Slightly pale yellow, Size: 1G
Supplier:
AOB CHEM USA
Description:
2-Fluoro-6-(trifluoromethyl)pyridine-3-boronic acid ≥97%
Supplier:
AMBEED, INC
Description:
3-Hydroxy-3-(trifluoromethyl)cyclobutanecarboxylic acid, Purity: 95%, CAS Number: 1163729-49-4, Appearance: Solid, Storage: Sealed in dry, Room Temperature, Size: 1G
Supplier:
AMBEED, INC
Description:
8-Methoxy-2-(trifluoromethyl)quinoline-5-carboxylic acid, Purity: 95%, CAS number: 199872-29-2, Appearance: Solid, Storage: Sealed in dry, Room Temperature, Size: 100MG
Supplier:
Thermo Scientific Chemicals
Description:
4,4,4-Trifluoro-3-methyl-2-butenoic acid. Grade: 96, Melting Point C28-30*. Boiling Point C: 158-163*. C5H5F3O2. 69056-67-3. CORROSIVE
Supplier:
AOB CHEM USA
Description:
3-(Methylthio)-5-(trifluoromethyl)benzoic acid ≥97%
Supplier:
AMBEED, INC
Description:
4-Methoxy-2-(trifluoromethyl)benzoic acid, Purity: 98%, CAS Number: 127817-85-0, Appearance: White to Yellow Solid, Storage: Sealed in dry, Room Temperature, Size: 250mg
Supplier:
AOB CHEM USA
Description:
4-(Trifluoromethyl)-1-benzothiophene-2-carboxylic acid ≥97%
Catalog Number:
(102836-542)
Supplier:
Matrix Scientific
Description:
3-{[4-(Trifluoromethyl)pyrimidin-2-yl]oxy}benzoic acid ≥97%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 006992-1G , MDL Number: MFCD01569538
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 024843-1G , MDL Number: MFCD01862052
Supplier:
Adipogen
Description:
Inhibitor of pan-Trk activity (IC(50) = 8 and 12nM for TrkA and TrkB). Shown to target Trk (tropomyosin receptor kinase) ATP binding cleft and an immediately adjacent hydrophobic pocket. Preferentially arrests the proliferation of Ba/F3 cells fused with Tel-TrkA, Tel-TrkB and Tel-TrkC (IC(50) = 11, 9 and 7nM, respectively) and in Ba/F3 and RIE cells expressing both TrkA and NGF (IC(50) = 42 and 17nM, respectively) over Mo7e-c-Kit and Rat-A10-PDGFR (IC(50) = 1 and 0.5µM) and Ba/F3-Tel-KDR and wt-Ba/F3 cells (IC(50) = 3.0 and 5.6µM). Displays ~100-fold greater selectivity among a panel of 59 closely related kinases and in 33 cellular kinase assays. Weakly active against relevant cytochrome P450 isozymes and hERG channel, and exhibit adequate microsomal stability, pharmacokinetic profile and efficacy in mice and rats. Suppresses tumor growth in a mouse RIE-TrkAmNGF xenograft model (50mg/kg, p.o.).
Supplier:
AMBEED, INC
Description:
3-Bromo-4-(trifluoromethyl)benzoic acid, Purity: 95%, CAS number: 581813-17-4, Appearance: White to Yellow Solid, Storage: Sealed in dry, Room Temperature, Size: 250MG
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