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2-Methoxyethyl+acetate
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2-Methoxyethyl+acetate
Supplier:
TCI America
Description:
CAS Number: 1906-82-7
MDL Number: MFCD00009173 Molecular Formula: C6H11NO3 Molecular Weight: 145.16 Purity/Analysis Method: >98.0% (N) Form: Crystal Boiling point (°C): 143 Melting point (°C): 47
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 009155-2.5G , MDL Number: MFCD01861160
Supplier:
APOLLO SCIENTIFIC
Description:
3-Bromo-5-(trifluoromethyl)phenylacetic acid 97%
Supplier:
AMBEED, INC
Description:
Glycocyamine 95%
Catalog Number:
(77439-970)
Supplier:
Bioss
Description:
Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses. Upon DNA damage, activates the promoter of the death-promoting transcription factor BCLAF1/Btf to trigger BCLAF1-mediated p53/TP53 gene transcription and apoptosis. In response to oxidative stress, interact with and activate CHUK/IKKA in the nucleus, causing the phosphorylation of p53/TP53. In the case of ER stress or DNA damage-induced apoptosis, can form a complex with the tyrosine-protein kinase ABL1 which trigger apoptosis independently of p53/TP53. In cytosol can trigger apoptosis by activating MAPK11 or MAPK14, inhibiting AKT1 and decreasing the level of X-linked inhibitor of apoptosis protein (XIAP), whereas in nucleus induces apoptosis via the activation of MAPK8 or MAPK9. Upon ionizing radiation treatment, is required for the activation of the apoptosis regulators BAX and BAK, which trigger the mitochondrial cell death pathway. Can phosphorylate MCL1 and target it for degradation which is sufficient to trigger for BAX activation and apoptosis. Is required for the control of cell cycle progression both at G1/S and G2/M phases. Mediates phorbol 12-myristate 13-acetate (PMA)-induced inhibition of cell cycle progression at G1/S phase by up-regulating the CDK inhibitor CDKN1A/p21 and inhibiting the cyclin CCNA2 promoter activity. In response to UV irradiation can phosphorylate CDK1, which is important for the G2/M DNA damage checkpoint activation. Can protect glioma cells from the apoptosis induced by TNFSF10/TRAIL, probably by inducing increased phosphorylation and subsequent activation of AKT1. Is highly expressed in a number of cancer cells and promotes cell survival and resistance against chemotherapeutic drugs by inducing cyclin D1 (CCND1) and hyperphosphorylation of RB1, and via several pro-survival pathways, including NF-kappa-B, AKT1 and MAPK1/3 (ERK1/2). Can also act as tumor suppressor upon mitogenic stimulation with PMA or TPA. In N-formyl-methionyl-leucyl-phenylalanine (fMLP)-treated cells, is required for NCF1 (p47-phox) phosphorylation and activation of NADPH oxidase activity, and regulates TNF-elicited superoxide anion production in neutrophils, by direct phosphorylation and activation of NCF1 or indirectly through MAPK1/3 (ERK1/2) signaling pathways. May also play a role in the regulation of NADPH oxidase activity in eosinophil after stimulation with IL5, leukotriene B4 or PMA. In collagen-induced platelet aggregation, acts a negative regulator of filopodia formation and actin polymerization by interacting with and negatively regulating VASP phosphorylation. Downstream of PAR1, PAR4 and CD36/GP4 receptors, regulates differentially platelet dense granule secretion; acts as a positive regulator in PAR-mediated granule secretion, whereas it negatively regulates CD36/GP4-mediated granule release. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.
Catalog Number:
(PI26102)
Supplier:
Invitrogen
Description:
SATA (and SATP) are reagents for introducing protected sulfhydryls into proteins, peptides and other molecules. for covalent modification of primary amines and addition of a protected sulphhydryl group.
Catalog Number:
(AAH26028-MD)
Supplier:
BeanTown Chemical
Description:
CAS: 125572-95-4; EC No: 236-308-9; MDL No: MFCD00066429
Solid; Molecular Formula: C14H22N2O8·H2O ; MW: 364.35
Melting Point: 213-216°
Supplier:
AMBEED, INC
Description:
Ethyl benzoylformate, Purity: 95%, CAS Number: 1603-79-8, Appearance: Form: liquid / Colour: Colorless - Yellow, Storage: Inert atmosphere, Room Temperature, Size: 25G
Catalog Number:
(TCT1226-010G)
Supplier:
TCI America
Description:
CAS Number: 40061-55-0
MDL Number: MFCD00017273 Molecular Formula: C11H14O2 Molecular Weight: 178.23 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Color: Colorless Boiling point (°C): 238 Flash Point (°C): 110 Specific Gravity (20/20): 1.01
Supplier:
Bachem Americas
Description:
Sequence: Boc-Gly-OH
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 024775-5G , MDL Number: MFCD00009120
Supplier:
AMBEED, INC
Description:
(3R,4R)-4-Acetoxy-3-[(R)-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone 97%
Catalog Number:
(100505-088)
Supplier:
R&D Systems
Description:
Endogenous potentiator, co-transmitter
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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