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2-Benzimidazolepropionic+acid
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2-Benzimidazolepropionic+acid
Supplier:
TCI America
Description:
CAS Number: 118949-61-4
MDL Number: MFCD00191815 Molecular Formula: C17H23N3O2 Molecular Weight: 301.39 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 152 Specific rotation [a]20/D: -120 deg (C=1, CH2Cl2)
Supplier:
AOB CHEM USA
Description:
2,6-Difluoro-3-(1-methylethoxy)-benzaldehyde ≥97%
Supplier:
AOB CHEM USA
Description:
1-(2,6-Difluorophenyl)-2,2-difluoroethanone ≥97%
Catalog Number:
(76791-988)
Supplier:
AMBEED, INC
Description:
2-Bromo-1-(2,6-dichlorophenyl)ethanone, Purity: 97%, CAS Number: 81547-72-0, Appearance: White to Yellow to Brown Solid or Liquid, Storage: Inert atmosphere, Room Temperature, Size: 250MG
Catalog Number:
(101879-196)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 047266-1G , MDL Number: MFCD08689758
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 043980-1G , MDL Number: MFCD04125008
Supplier:
PeproTech, Inc.
Description:
Sclerostin, a glycoprotein predominantly secreted by osteocytes, is a member of the Cerberus/DAN family of putative BMP antagonists that functions as an endogenous regulator of the canonical Wnt signaling pathway and an inhibitory regulator of bone homeostasis. Although expressed nearly exclusively by osteocytes, sclerostin can also be found at significant levels elsewhere, such as bone, bone marrow, cartilage, the kidney, and the liver, and has also been shown to be produced by hypertrophic chondrocytes and cementocytes. Like DKK family members DKK-1 and DKK-4, sclerostin plays an important regulatory role in the Wnt/beta-catenin signaling pathway by forming inhibitory complexes with LDL Receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/beta-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/beta-catenin signaling cascade. Sclerostin has also been shown to interact directly with LRP4 via its extracellular domain to facilitate inhibition of Wnt signaling, and can catabolically promote osteoclast activity by increasing osteocyte expression of RANKL. Sclerostin's critical involvement in the regulation of bone formation and resorption is emphasized by two bone dysplasia disorders, sclerosteosis and van Buchem disease (VBD), caused by rare autosomal recessive mutations that result in progressive bone overgrowth and hypermineralization due to markedly decreased sclerostin levels. PeproTech's CHO cell-derived Recombinant Human Sclerostin is a 190-amino-acid-length glycoprotein with a calculated molecular weight of 21.5 kDa. As a result of glycosylation, Recombinant Human Sclerostin migrates with an apparent molecular mass of approximately 28-35 kDa by SDS-PAGE gel, under non-reducing conditions.
Supplier:
AMBEED, INC
Description:
2-(4-Bromo-2,6-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, Purity: 99% HPLC, CAS Number: 1799485-20-3, Appearance: Pale-yellow to Yellow-brown Liquid, Storage: Inert atmosphere, 2-8C, Size: 25G
Supplier:
AOB CHEM USA
Description:
Methyl 2,6-dichloro-3-isopropoxybenzoate ≥97%
Supplier:
AMBEED, INC
Description:
1-(3-Amino-2,6-dichloropyridin-4-yl)ethanone, Purity: 97%, CAS number: 912772-91-9, Appearance: solid, Storage: Keep in dark place, Inert atmosphere, 2-8C, Size: 1G
Supplier:
AMBEED, INC
Description:
(S)-3-(1-Oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione benzenesulfonate, Purity: 97%, CAS Number: 2229714-16-1, Appearance: Solid, Storage: Inert atmosphere, 2-8C, Size: 250MG
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 009313-1G , MDL Number: MFCD00007678
Catalog Number:
(101781-358)
Supplier:
Matrix Scientific
Description:
MF=C6H3Cl2F3N2 MW=231.01 Cas=175277-67-5 MDL=MFCD00173957 ,500Mg
Supplier:
AMBEED, INC
Description:
2-(4-Chloro-2,6-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, Purity: 98%, CAS Number: 1165935-84-1, Appearance: Colorless to Yellow Liquid or Semi-Solid or solid, Storage: Inert atmosphere, 2-8C, Size: 250MG
Supplier:
AOB CHEM USA
Description:
Methyl 2,6-dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate ≥97%
Supplier:
AOB CHEM USA
Description:
Ethyl 2-(2,6-difluoro-3-(trifluoromethyl)phenyl)-2-oxoacetate ≥95%
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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