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1-(6-Nitropyridin-3-yl)piperazine


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Supplier:  MP Biomedicals
Description:   Clomiphene Citrate Salt is a mixture of cis- and trans- isomers. Clomiphene citrate is a selective estrogen receptor modulator.
Catalog Number: (IC15588125)

Supplier:  MP Biomedicals
Description:   Nitrofurantoin is an antibactericidal compound that has been historically prepared by the reaction of 1-aminohydantoin sulphate and 5-nitro-2-furaldehyde diacetate.
MSDS SDS
Supplier:  Adipogen
Description:   Immunosuppressant. Calcineurin inhibitor with lower activity than Cyclosporin A (AG-CN2-0079). Antifungal. Antitumor.
Catalog Number: (80055-990)

Supplier:  MilliporeSigma
Description:   Inhibitor of calpain I (Ki=120nM), calpain II (Ki=230nM), cathepsin B (Ki=100nM), and cathepsin L (Ki=0.6nM). Inhibits activation-induced programmed cell death and restores defective immune responses in HIV+ donors. Also prevents nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene.
Supplier:  Adipogen
Description:   TAE684 is a potent and selective ALK inhibitor with an IC(50) of 3nM. It is 100-fold more sensitive for ALK over InsR.
Supplier:  Adipogen
Description:   Potent cell permeable JAK3 inhibitor (IC50 = 1nM). Shows also JAK-1 inhibitory activity. Immunosuppressive and anti-inflammatory agent. Inhibits signaling through heterodimeric receptors associated with JAK3, JAK1, or both of them, with functional selectivity over JAK2-paired receptors. Blocks downstream STAT signaling, resulting in potent inhibition of several cytokines, including interleukins 2, 4, 7, 9, 15 and 21, which are integral to lymphocyte activation, function and proliferation. Investigated for several autoimmune disorders including, rheumatoid arthritis and psoriasis. Potent and selective inhibitor of HIV-1 replication and virus reactivation in vitro.
Supplier:  Adipogen
Description:   Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC(50) values of 0.6µM, 0.1µM and 0.1µM, respectively.
Supplier:  Adipogen
Description:   PF-562,271 is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 catalytic activity with a IC(50) of 1.5 and 14nM, respectively. In addition, PF-562,271 displayed robust inhibition in an inducible cell-based assay measuring phospho-FAK with an IC(50) of 5nM. PF-562,271 was evaluated against multiple kinases and displays <gt/>100x selectivity against a long list of nontarget kinases. In tests, PF-562,271 inhibits FAK phosphorylation in vivo in a dose-dependent fashion with a calculated EC50 of 93ng/mL using injections.
Supplier:  VWR International
Description:   Designed for labs and plant processes where multiple gases are used.
Supplier:  MP Biomedicals
Description:   Tannic Acid is used for enzyme immobilization and protein adsorption
MSDS SDS
Supplier:  MilliporeSigma
Description:   Clear liquid. For low level trace metal analysis. Double-distilled and packaged in Class 10 cleanroom conditions. Certificate of analysis supplied with each shipment.
MSDS SDS
Supplier:  Adipogen
Description:   The reagent, a cyanine dye, can be used as a label for the determination of proteins with NIR-fluorescent technology. The absorption-maxima of the reagent lies in a region of low interference by other biomolecules. The isothiocyanate-moiety is used to link the reagent to proteins which can sensitively be detected. Experiments to lower the detection-limits of immunoassays have been done.
Catalog Number: (89259-878)

Supplier:  VWR International
Description:   VWR® Pinch Clamps for glass ball and socket or O-ring joints add convenience and speed in mounting and dismantling a glass apparatus.
Supplier:  Adipogen
Description:   Checkpoint kinases CHK1 and CHK2 are activated in response to DNA damage that results in cell cycle arrest, allowing sufficient time for DNA repair. Agents that lead to abrogation of such checkpoints have potential to increase the efficacy of such compounds as chemo- and radiotherapies. AZD7762 is a specific inhibitor for the CHK1/2 kinases with IC(50) values less than 10. AZD7762 enhances radiation sensitivity and gemcitabine-mediated radiosensitization in pancreatic cancer cells and xenografts and thus is helpful in the treatments of potentially many cancers. In addition, AZD7762 is a chemosensitizer and with gemcitabine and radiation produced a significant delay in the growth of pancreatic tumor xenografts with tolerable toxicity. AZD7762 is being studied as an important link in improving both adjuvant therapy and the treatment of metastatic disease.
Supplier:  Adipogen
Description:   Steroidal prohormone of the major insect molting hormone 20-hydroxyecdysone. A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. Induces the expression of genes coding for proteins that the larva requires, and it causes chromosome puffs (sites of high expression) to form in polytene chromosomes. Plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in moulting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP). Appears in many plants mostly as a protection agent (toxins or antifeedants) against herbivorous insects. Used for controlled gene expression in scientific research, agriculture and medicine. Used for the development of selective insect growth regulators for use as environmentally benign insecticides.

Supplier:  MP Biomedicals
Description:   Cyproheptadine is a Ca2+ channel blocker; 5-HT2 serotonin receptor antagonist; antihistamine, antipruritic. It is a migraine prophylactic.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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