Supplier:
Matrix Scientific
Description:
MF=C11H11Bro5 MW=303.12 MDL=MFCD20444444 1G
Supplier:
Matrix Scientific
Description:
MF=C14H19NO3 MW=249.31 CAS=193964-75-9 MDL=MFCD22126102 500MG
Supplier:
TCI America
Description:
CAS Number: 7377-26-6
MDL Number: MFCD00059486 Molecular Formula: C9H7ClO3 Molecular Weight: 198.60 Purity/Analysis Method: >95.0% (GC) Form: Crystal Color: White Boiling point (°C): 140 Melting point (°C): 54
Catalog Number:
(101814-240)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 022541-500MG , MDL Number: MFCD08688155
Supplier:
TCI America
Description:
CAS Number: 3204-73-7
MDL Number: MFCD00075872 Molecular Formula: C10H12O4 Molecular Weight: 196.20 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 66
Catalog Number:
(TCD1848-025G)
Supplier:
TCI America
Description:
CAS Number: 67362-76-9
MDL Number: MFCD00055652 Molecular Formula: C15H23NO3 Molecular Weight: 265.35 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Flash Point (°C): 250 Specific Gravity (20/20): 1.05
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 051735-500MG , MDL Number: MFCD13343616
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 063296-500MG , MDL Number: MFCD04082979
Supplier:
Adipogen
Description:
AT7519 is a potent inhibitor of several CDK family members. AT7519 showed potent antiproliferative activity (40-940nM) in a panel of human tumor cell lines, and the mechanism of action was shown here to be consistent with the inhibition of CDK1 and CDK2 in solid tumor cell lines. AT7519 caused cell cycle arrest followed by apoptosis in human tumor cells and inhibited tumor growth in human tumor xenograft models. Tumor regression was observed following twice daily dosing of AT7519 in the HCT116 and HT29 colon cancer xenograft models. Also it has been shown that the biological effects are linked to inhibition of CDKs in vivo and that AT7519 induces tumor cell apoptosis in these xenograft models. Moreover, AT7519 has an attractive biological profile and is well tolerated and effective making it a more plausible candidate for clinical development than previously available CDK inhibitors. In in vitro kinase assays AT7519 showed nanomolar levels of activity from <lt/>10 to 2400 for cyclins; only one other non-cyclin related kinase was inhibited at levels below 10µM (GSK3beta, 89nM), all others tested had IC(50)'s of greater than 10,000nM.
Catalog Number:
(TCD1899-100G)
Supplier:
TCI America
Description:
CAS Number: 6638-79-5
MDL Number: MFCD00012485 Molecular Formula: C2H7NO Molecular Weight: 97.54 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 115
Supplier:
AMBEED, INC
Description:
Methyl 3-(((tert-butoxycarbonyl)amino)methyl)benzoate, Purity: 97%, CAS Number: 180863-55-2, Appearance: White to off-white solid, Storage: Sealed in dry, 2-8C, Size: 100MG
Supplier:
TCI America
Description:
CAS Number: 10017-11-5
MDL Number: MFCD00054329 Molecular Formula: C3H7N Molecular Weight: 93.55 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 106
Supplier:
TCI America
Description:
CAS Number: 67-03-8
MDL Number: MFCD00012780 Molecular Formula: C12H17ClN4OS Molecular Weight: 337.26 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Color: White
Supplier:
TCI America
Description:
Methyl Pipecolinate Hydrochloride, Purity: >98.0%(T), CAS Number: 32559-18-5, MF: C7H13NO2.HCl, Molecular Weight: 179.64, Synonyms: Methyl 2-Piperidinecarboxylate Hydrochloride, Pipecolinic Acid Methyl Ester Hydrochlorid, 2-Piperidinecarboxylic Acid, Size: 1G
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 044666-1G , MDL Number: MFCD00831780
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