2-Formyl-4-methylthiophene-3-carboxylic+acid
Supplier:
AMBEED, INC
Description:
2-(3-(Bromomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 98%
Supplier:
Matrix Scientific
Description:
MF=C7H8BRNO2S MW=250.12 CAS=40724-47-8 MDL=MFCD08752696 5G
Supplier:
AMBEED, INC
Description:
2-(Bromomethyl)-4-fluorophenylboronic acid neopentyl glycol ester 98%
Supplier:
AMBEED, INC
Description:
4-Bromomethyl-1,2-dihydroquinoline-2-one 97%
Supplier:
TCI America
Description:
CAS Number: 2417-72-3
MDL Number: MFCD00032453 Molecular Formula: C9H9BrO2 Molecular Weight: 229.07 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 56
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Appearance: Clear colorless to light brown Liquid
Supplier:
AMBEED, INC
Description:
2-(4-(Bromomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 97%
Catalog Number:
(102842-180)
Supplier:
Matrix Scientific
Description:
4-(Bromomethyl)thiazole ≥95%
Catalog Number:
(102519-578)
Supplier:
Matrix Scientific
Description:
MF=C7H5BR3 MW=328.84 CAS=93701-32-7 MDL=MFCD13185505 5G
Supplier:
Matrix Scientific
Description:
MF=C10H8BRNO MW=238.09 CAS=4876-10-2 MDL=MFCD03426152 10G
Supplier:
TCI America
Description:
CAS Number: 114772-38-2
MDL Number: MFCD06200816 Molecular Formula: C15H13BrO2 Molecular Weight: 305.17 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 56
Catalog Number:
(101796-858)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 009320-1G , MDL Number: MFCD04037923
Supplier:
TCI America
Description:
CAS Number: 4224-69-5
MDL Number: MFCD00011697 Molecular Formula: C5H7BrO2 Molecular Weight: 179.01 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 42 Flash Point (°C): 78 Specific Gravity (20/20): 1.50 Storage Temperature: 0-10°C
Catalog Number:
(10319-736)
Supplier:
Bioss
Description:
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilize XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Supplier:
AMBEED, INC
Description:
tert-Butyl-4-(bromomethyl)piperidine-1-carboxylate 97%, Ambeed.Inc
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