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4,4-Dimethylpyrrolidine-3-carboxylic acid hydrochloride
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4,4-Dimethylpyrrolidine-3-carboxylic acid hydrochloride
Supplier:
Adipogen
Description:
Tozasertib, or VX-680, is a potent and selective inhibitor of Aurora kinases, particularly Aurora A and B. In vitro, VX-680 blocks cell cycle progression and induces apoptosis in a wide range of human tumor types at low IC(50) values (i.e. 3.38nM for human BE-13 cells, and 14.34nM for NTERA cells). Moreover, VX680, also has very potent Ki values, with inhibition constants (Ki) of 0.6, 18, and 46nM for Aurora A, B, and C, respectively. VX-680 is also effective in vivo, being used in a Caki-1 xenograft model, VX-680 demonstrated a 75.7% (P < 0.001) decrease in Caki-1 xeno-graft tumor volume with no apparent alternation in animal body weight, peripheral blood counts, or other biological parameters.
Supplier:
VWR
Description:
IPTG (isopropyl-β-D-thiogalactopyranoside) ≥99.0%, Ultra Pure Grade
Supplier:
AMBEED, INC
Description:
2-(Tetrahydro-2H-pyran-4-yl)acetonitrile, Purity: 97%, CAS Number: 850429-50-4, Appearance: Liquid, Storage: Sealed in dry, Room Temperature, Size: 5g
Supplier:
AMBEED, INC
Description:
Ethyl 2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-thio-beta-D-glucopyranoside, Purity: 98%, CAS Number: 130539-43-4, Appearance: Solid, Storage: Inert atmosphere, 2-8 C, Size: 1g
Catalog Number:
(102845-314)
Supplier:
Matrix Scientific
Description:
5,6-Dichloro-1,3-dihydro-2H-benzimidazol-2-one ≥95%
Catalog Number:
(77407-464)
Supplier:
APOLLO SCIENTIFIC
Description:
2H-Thieno[3,2-d][1,3]oxazine-2,4(1H)-dione
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 052635-2.5G , MDL Number: MFCD13562326
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Rhodium(II) acetate dimer dihydrate ca 43% Rh
Catalog Number:
(101932-226)
Supplier:
Matrix Scientific
Description:
MF=C12H12Fn3 MW=217.25 Cas=916423-12-6 MDL=MFCD09258791 ,250Mg
Supplier:
AMBEED, INC
Description:
2-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid, Purity: 95%, CAS Number: 4113-97-7, Appearance: White to off-white powder or crystals, Storage: Inert atmosphere, Room Temperature, Size: 250mg
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 044505-1G , MDL Number: MFCD01936013
Supplier:
Matrix Scientific
Description:
MF=C5H7Fo2 MW=118.11 Cas=624734-19-6 1G
Supplier:
Thermo Scientific Chemicals
Description:
1g CAS: 4430-75-5, MDL: MFCD01098257
Catalog Number:
(101850-706)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041053-500MG , MDL Number: MFCD12028502
Catalog Number:
(101929-784)
Supplier:
Matrix Scientific
Description:
MF=C9H10N2O MW=162.19 Cas=10045-45-1 MDL=MFCD00005715 500Mg
Catalog Number:
(101824-550)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 027626-500MG , MDL Number: MFCD02656552
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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