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Bis(tributyltin)+oxide


20,296  results were found

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Supplier:  Matrix Scientific
Description:   Matrix Scientific Part Number: 008804-25G , MDL Number: MFCD00042167
Supplier:  AMBEED, INC
Description:   N,N'-Bis(2-hydroxybenzyl)ethylenediamine 98%
Supplier:  Matrix Scientific
Description:   Bis(aminoguanidinium) sulfate ≥97%
Supplier:  Bioss
Description:   ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.
Catalog Number: (10297-806)

Supplier:  Bioss
Description:   Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
Supplier:  Bioss
Description:   FOXO1 is a transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and STK4/MST1. Promotes neural cell death. Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.

FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.

Supplier:  Prosci
Description:   Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
Supplier:  AMBEED, INC
Description:   Bis(vinylsulfonyl)methane 98%
Supplier:  TCI America
Description:   Bis(4-formylphenyl) Ether, Purity: >98.0%(GC), CAS Number: 2215-76-1, Molecular Formula: C14H10O3, Molecular Weight: 226.23, Synonyms: 4,4'-Diformyldiphenyl Ether, 4,4'-Oxydibenzaldehyde, Size: 5G
Supplier:  BeanTown Chemical
Description:   CAS: 12030-88-5; EC No: 234-746-5; MDL No: MFCD00082411 UN No: UN2466; Haz Class: 5.1; Packing Group: I 2-10 Micron Powder; Molecular Formula: KO2; MW: 71.10 Melting Point: 400° Density (g/mL): 2.14
MSDS SDS
Supplier:  Strem Chemicals Inc
Description:   Phosphine
Supplier:  Matrix Scientific
Description:   Matrix Scientific Part Number: 008809-5G , MDL Number: MFCD01940963
Supplier:  AOB CHEM USA
Description:   2,6-Bis(benzyloxy)pyridine ≥97%
Supplier:  TCI America
Description:   1-Methyl-1-pentylpyrrolidinium bis(trifluoromethanesulfonyl)imide ≥98.0% (by titrimetric analysis)
Supplier:  AMBEED, INC
Description:   1,2-Bis(4-bromophenyl)disulfane 98%
New Product
Supplier:  Diagnostic Biosystems
Description:   P504S has been recently described as a prostate cancer-specific gene that encodes a protein involved in the β-oxidation of branched chain fatty acids. Expression of p504S protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. P504S can be used as a positive marker for PIN.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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