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Copper(II)+trifluoroacetate+hydrate
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Copper(II)+trifluoroacetate+hydrate
Supplier:
Bachem Americas
Description:
CART (Cocaine- and Amphetamine-Regulated Transcript) is a recently discovered peptide, which was initially identified as mRNA produced primarily in the rat hypothalamus after administration of psychomotor stimulants. It is a satiety factor and closely associated with the actions of two important regulators of food intake, leptin and neuropeptide Y. When systemic leptin or receptors for leptin are inhibited, expression of CART mRNA is suppressed. CART (55-102) has been isolated from the hypothalamus of ovine suggesting in vivo processing at the Lys⁵³-Arg⁵⁴ region. When injected intracerebroventricularly into rats, recombinant CART peptides inhibited both normal and starvation-induced feeding, and completely blocked the feeding response induced by neuropeptide Y. Thus far, CART (55-102) appears to be the most potent fragment with a conserved secondary structure consisting of three disulfide bridges. Disruption of this secondary structure by reduction leads to a loss of the appetite induction.
Catalog Number:
(89297-274)
Supplier:
Genetex
Description:
Goat polyclonal antibody to AOC3
Catalog Number:
(H-6334.0500BA)
Supplier:
Bachem Americas
Description:
Small synthetic molecules called growth-hormone secretagogues (GHSs) stimulate the release of growth hormone (GH) from the pituitary through a G protein-coupled receptor (GHS-R). Recently, ghrelin ("ghre" is the Proto-Indo-European root of the word "grow") has been identified as an endogenous ligand for GHS-R. These peptides consist of 28 amino acids with an octanoyl-residue at Ser³, which is essential for expressing activity. Ghrelin stimulates GH release from rat primary culture pituitary cells in a dose-dependent manner and induces an increase in intracellular Ca²⁺ in GHS-R-expressing cells with an EC₅₀ value of 2.5 nM. Human ghrelin is homologous to rat ghrelin apart from two amino acids. The occurrence of ghrelin in both rat and human indicates that GH release from the pituitary may be regulated not only by hypothalamic GHRH, but also by ghrelin. In future, ghrelin might be used in the treatment of aging patients as well as in patients with idiopathic GH deficiency, obesity, osteoporosis or cardiovascular diseases.
Catalog Number:
(BDH7590-2)
Supplier:
VWR International
Description:
Suitable as a titrant. Made with deionized water.
Supplier:
Bachem Americas
Description:
Highly potent and selective β-MSH-derived melanocortin-4 receptor (MC-4R) agonist with sub-nanomolar potency. The binding affinities for human MC-4R, MC-1R, MC-3R and MC-5R were 0.55 ± 0.06, 16.78 ± 1.53, 56.79 ± 4.66, and < 500 nM, respectively. Daily subcutaneous injection of H-6268 to diet-induced obese rats over a period of 14 days demonstrated an effect on reduction of fat mass.
Supplier:
Electron Microscopy Sciences
Description:
Veco Grids offer superior handling characteristics. Plus, with a 0.8 mil thickness, a most rigid grids available.
Catalog Number:
(10475-346)
Supplier:
Bioss
Description:
COMMD is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. Down-regulates activation of NF-kappa-B.
Supplier:
Electron Microscopy Sciences
Description:
Thin film of pure formvar resin coats the shiny side of a London finder grids.
Catalog Number:
(BDH9300-500G)
Supplier:
VWR International
Description:
Meets reagent specifications for testing USP/NF monographs.
Supplier:
ALADDIN SCIENTIFIC
Description:
Application:2-Amino-3-bromopyridine may be used to synthesize:2-acylamido-3-bromopyridines；2-anilino-3-bromopyridine；3-[(2-methoxyphenyl)ethynyl]pyridin-2-amine；3-[(4-methoxyphenyl)ethynyl]pyridin-2-amine；N-(bromopyridyl)amidines；carbolines via palladium catalyzed arylation followed by palladium catalyzed amination reaction；2-amino-3-cyanopyridine via palladium catalyzed cyanation reaction with potassium ferro-cyanide in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene [DBU]；nitro-substituted N,N′-dipyridinylamines via palladium catalyzed coupling reaction with 2-chloro-3-nitropyridine in the presence of Xantphos ligand；2-amino-3-iodopyridine via reaction with sodium iodide in the presence of copper(I)iodide and trans-N,N′-dimethylcyclohexane-1,2-diamine；
Catalog Number:
(10253-866)
Supplier:
Bioss
Description:
Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
Supplier:
Electron Microscopy Sciences
Description:
A thin film of pure formvar resin coats the shiny side of a thin bar hexagonal grid.
Supplier:
Electron Microscopy Sciences
Description:
A thin film of pure formvar resin coats the shiny side of a Single Hole grid.
Supplier:
Electron Microscopy Sciences
Description:
As an acidic dispersion, Colloidal Alumina is a chemical-mechanical action, that provides superior surfaces on germanium, silicon, gallium arsenide, zinc sulphide, fluorides, sapphire, ferrite's and silicon carbide. Low scatter finishes can be obtained on pure metals such as nickel, tungsten, copper, beryllium, steel and aluminum. Epoxy resin materials and plastics have also been successfully polished with this versatile colloidal dispersion.
Catalog Number:
(BDH9288-2.5KG)
Supplier:
Bachem Americas
Description:
Small synthetic molecules called growth-hormone secretagogues (GHSs) stimulate the release of growth hormone (GH) from the pituitary through a G protein-coupled receptor (GHS-R). Recently, ghrelin ("ghre" is the Proto-Indo-European root of the word "grow") has been identified as an endogenous ligand for GHS-R. These peptides consist of 28 amino acids with an octanoyl-residue at Ser³, which is essential for expressing activity. Ghrelin stimulates GH release from rat primary culture pituitary cells in a dose-dependent manner and induces an increase in intracellular Ca²⁺ in GHS-R-expressing cells with an EC₅₀ value of 2.5 nM. Human ghrelin is homologous to rat ghrelin apart from two amino acids. The occurrence of ghrelin in both rat and human indicates that GH release from the pituitary may be regulated not only by hypothalamic GHRH, but also by ghrelin. In future, ghrelin might be used in the treatment of aging patients as well as in patients with idiopathic GH deficiency, obesity, osteoporosis or cardiovascular diseases.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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