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Dibutyryl-cGMP
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Dibutyryl-cGMP
Supplier:
PROTIDE PHARMACEUTICALS
Description:
A unique cryopreservation solution that does not contain DMSO, fetal bovine serum, or animal protein. pZerveâ„¢ is ready to use and does not require any dilution or further processing.
Catalog Number:
(77439-150)
Supplier:
Bioss
Description:
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Catalog Number:
(89157-838)
Supplier:
Enzo Life Sciences
Description:
General, cell permeable protein kinase inhibitor. Acts by binding to the ATP binding domain of the kinase. Potent inhibitor of Ca2+/calmodulin kinase II. Inhibits myosin light chain kinase (MLCK; Ki=0.147µM), cAMP- dependent protein kinase (PKA; Ki=0.09µM), protein kinase C (PKC; Ki=0.02µM), and cGMP-dependent protein kinase (PKG; Ki=0.1µM).
Catalog Number:
(76014-712)
Supplier:
Spectrum Chemicals
Description:
Oxytocin, USP is a drug used to induce labor. All Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Supplier:
GE Healthcare - HyClone
Description:
Supplements cell culture with amino acids, vitamins, glucose, trace elements, and growth factors. Manufactured to meet cGMP manufacturing standards and QC specifications.
Supplier:
Adipogen
Description:
Potent and highly selective, irreversible inhibitor of soluble guanylyl cyclase (sGC). The binding is competitive with nitric oxide (NO). Tool to elucidate the nitric oxide (NO)-cGMP pathway. Apoptosis inhibitor Inhibits growth and migration of prostate cancer cells independent of its effects on GMP levels.
Catalog Number:
(75788-988)
Supplier:
Prosci
Description:
Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions, such as diuresis, natriuresis, vasorelaxation, which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water, improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3.
Catalog Number:
(76545-824)
Supplier:
NANOENTEK USA INC.
Description:
ADAMâ„¢ CellT is an automated cell counter that complies with the 21 CFR Part 11 which is a regulation on electronic records and signatures for use in cGMP facilities. Data cannot be modified by any user. Every action of users is recorded in an audit trail which includes the date, time, and specific details of the action.
Supplier:
Spectrum Chemicals
Description:
Methylcellulose, USP is a bulk-forming laxative. All Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Supplier:
Molecular Devices
Description:
IMAP® technology provides a homogeneous assay applicable to a wide variety of kinases without regard for substrate peptide sequence.
Supplier:
Charles River Laboratories Cell Solutions
Description:
Human peripheral blood mononuclear cells (PBMC) are collected from healthy human volunteer donors following cGMP and cGTP collection guidelines under IRB approved informed consent by leukapheresis using the COBE® Spectra Apheresis System MNC collection protocol
Supplier:
Spectrum Chemicals
Description:
Hydroxypropyl Methylcellulose, 4,000 cP, FCC is most commonly used as an alternative to gelatin and gluten and is approved by FDA as both a direct and an indirect food additive. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Catalog Number:
(10300-328)
Supplier:
Bioss
Description:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble forms, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor forms, known as GC, are peptide hormone receptors. GCS, a cGMP-synthesizing enzyme, is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one alpha subunit, designated GCS-alpha-1, and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both the alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity.
Supplier:
Spectrum Chemicals
Description:
Iodine, Resublimed (DEA List I Chemical), Crystal, USP is a chemical element and it is often found as a contrast material in X-rays and water purification reagents.
Catalog Number:
(10168-818)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to PDE6 delta
Supplier:
Spectrum Chemicals
Description:
Aluminum Monostearate, NF is also known as Dihydroxyaluminum stearate.Â
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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