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Dibutyryl-cGMP
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Dibutyryl-cGMP
Catalog Number:
(MSPP-100-0956)
Supplier:
Stemcell Technologies
Description:
cGMP, serum-free, and xeno-free medium for the expansion of human T cells.
Catalog Number:
(101106-544)
Supplier:
Enzo Life Sciences
Description:
Cyclic GMP (cGMP), which has been shown to be present at levels typically 10-100 fold lower than cAMP, is formed by the action of the enzyme guanylate cyclase on GTP. Some hormones, such as Acetylcholine, Insulin, and Oxytocin, as well as certain other chemicals like Serotonin and Histamine cause an increase in cGMP levels. Stimulators of guanylate cyclase such as the vasodilators nitroprusside, nitroglycerin, sodium nitrate, and nitric oxide (NO) also stimulate cGMP levels.
Catalog Number:
(77523-718)
Supplier:
AFG BIOSCIENCE LLC
Description:
Mouse PRKG1 (Protein Kinase, cGMP Dependent Type I) ELISA Kit
Supplier:
Bachem Americas
Description:
The ANP antagonist A71915 inhibits ANP-induced cGMP stimulation.
Supplier:
Avantor Performance Materials
Description:
Suitable for bioprocessing. BSE/TSE free. Endotoxin tested. Custom packaging and testing available. Change management and notification available. Samples available.
Catalog Number:
(77519-470)
Supplier:
AFG BIOSCIENCE LLC
Description:
Human PRKG2 (Protein Kinase, cGMP Dependent Type II) ELISA Kit
Catalog Number:
(10331-868)
Supplier:
Bioss
Description:
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP (PubMed:9714779, PubMed:15489334). Specifically regulates nitric-oxide-generated cGMP (PubMed:15489334).
Catalog Number:
(77528-358)
Supplier:
AFG BIOSCIENCE LLC
Description:
Human PDE9A (High affinity cGMP-specific 3′,5′-cyclic phosphodiesterase 9A) ELISA Kit
Catalog Number:
(89367-374)
Supplier:
Genetex
Description:
The cyclic monophosphate nucleotides (cyclic adenosine monophosphate [cAMP] and cyclic guanosine monophosphate [cGMP]) are found ubiquitously in mammalian cells and act as second messenger transducers to effect the intracellular actions of a variety of G protein coupled receptors (GPCRs) for hormones, cytokines, and neurotransmitters. Cyclic nucleotides are important intracellular second messengers which play important role in a variety of signal transduction process. The cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodieterases. One of the many phosphodiesterases that compartmentalized and hydrolyze cGMP in various tissues is phosphodiesterase type 5A. The cGMP is involved in nitric oxide signaling as well as cell signaling associated with natriuretic peptides and gulanylins. Some of the intracellular biding cites for the cGMP include cyclic nucleotide gated ion channels, cGMP dependent protein kinases, and cyclic GMP biding phosphodiesterases (cGB PDEs). The cGB PDEs include PDE2, PDE3, PDE5, PDE5 and PDE10; the members of these families contain various structural and functional motifs that are conserved. Most of these proteins contain dimmeric subunits that contain a highly conserved cGMP binding site and a phosphodiesterase catalytic site.
Catalog Number:
(MSPP-10990)
Supplier:
Stemcell Technologies
Description:
cGMP, human T cell activation and expansion reagent.
Catalog Number:
(89367-338)
Supplier:
Genetex
Description:
Cyclic nucleotides are important intracellular second messengers which play an important role in a variety of signal transduction process. The cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodiesterases. One of the many phosphodiesterases that compartmentalize and hydrolyze cAMP and cGMP into AMP and GMP is PDE2. Two genes, PDE2A and PDE2B, have been identified and cloned and they both have an apparent molecular weight of 100 kDA. PDE2A has specificity for cAMP and its activity is modulated by the presence of cGMP. In contrast, PDE2B does not hydrolyze cGMP nor its activity is altered by the presence of cGMP. Western blot analyses of PDE2A reveals that it is present in a variety of tissues including neocortex, cerebellum, heart, kidney lungs, pulmonary artery and skeletal muscle.
Catalog Number:
(89161-370)
Supplier:
Enzo Life Sciences
Description:
Ultrapotent, highly selective inhibitor of cGMP-inhibited phosphodiesterase (PDE lll, IC50=0.3nM) in vitro. Potentiates adenosine-stimulated cAMP accumulation.
Supplier:
Stemcell Technologies
Description:
cGMP, feeder-free maintenance medium for human ES and iPS cells.
Supplier:
Spectrum Chemicals
Description:
Syrup, NF is a thick, viscous sweetened liquid vehicle for pharmaceutical formulations. All Spectrum Chemical NF grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Avantor excipients are used during the formulation process in a wide range of applications. Avantor provides high-purity and performance excipients that serve as fillers, binders, disintegrants, lubicants, flavors, emulsifiers and preservatives. All the products are cGMP produced and meet USP grade standards.
Catalog Number:
(80052-178)
Supplier:
MilliporeSigma
Description:
A major oxygen-transporting component of red blood cells. A nitric oxide scavenger. Blocks carbachol-stimulated cGMP production. This preparation contains primarily ferric-hemoglobin and must be reduced to the ferrous form to bind molecular oxygen.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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