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3-Amino-3-(3-cyclohexenyl)propanoic+acid
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3-Amino-3-(3-cyclohexenyl)propanoic+acid
Supplier:
AMBEED, INC
Description:
3,5-Dibromobenzene-1-sulfonyl chloride 97%
Catalog Number:
(100264-646)
Supplier:
Indofine Chemical Company
Description:
Herbal Standards 134-04-3 10mg 3,5,7,4'-Tetrahydroxyflavylium chloride 306.71 Hydroscopic.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Benzalkonium chloride alkyl distribution from C8H17 to C16H33
Catalog Number:
(EM8.00236.0100)
Supplier:
AMBEED, INC
Description:
2-Methyl-5-nitrobenzenesulfonyl chloride 98%
Catalog Number:
(10352-656)
Supplier:
Bioss
Description:
Key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction via both the virus-activated, MyD88-independent pathway and the TLR-activated, MyD88-dependent pathway. Required during both the early and late phases of the IFN gene induction but is more critical for the late than for the early phase. Exists in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, becomes phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization and nuclear localization where along with other coactivators it can activate transcription of the type I IFN and ISG genes. Can also play a role in regulating adaptive immune responses by inducing PSMB9/LMP2 expression, either directly or through induction of IRF1. Binds to the Q promoter (Qp) of EBV nuclear antigen 1 a (EBNA1) and may play a role in the regulation of EBV latency. Can activate distinct gene expression programs in macrophages and regulate the anti-tumor properties of primary macrophages.
Catalog Number:
(10081-674)
Supplier:
Proteintech
Description:
NFkB is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFkB is activated by various intra- and extracellular stimuli such as cytokines, oxidant free radicals, ultraviolet irradiation, and bacterial or viral products. NFkB is a family of transcription factors that consists of homo- and heterodimers of NFkB1/p50 and RelA/p65 subunits, and controls a variety of cellular events including development and immune responses. All members share a conserved amino terminus domain that includes dimerization, nuclear localization, and DNA binding regions, and a carboxy terminal transactivation domain. Serines 529 and 536 in the transactivation domain of RelA/p65 are phosphorylated in response to several stimuli including phorbol ester, IL1 alpha and TNF alpha as mediated by IkB kinase and p38 MAPK. Phosphorylation of serines 529 and 536 is critical for RelA/p65 transcriptional activity. Activated NFkB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFkB has been associated with a number of inflammatory diseases while persistent inhibition of NFkB leads to inappropriate immune cell development or delayed cell growth. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing. This antibody can bind both p105 and p50 isoforms of NFKB1.
Supplier:
APOLLO SCIENTIFIC
Description:
(Methoxymethyl)triphenylphosphonium chloride 98%
Supplier:
APOLLO SCIENTIFIC
Description:
2-Fluoro-4-methylbenzenesulfonyl chloride
Catalog Number:
(TS42785-1000)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Trimethyltin chloride 20% (w/w) 1 M in THF, AcroSeal™
Catalog Number:
(102898-406)
Catalog Number:
(102898-064)
Supplier:
Spectrum Chemicals
Description:
Storage temperature - HYGROSCOPIC: Keep tightly closed.
Supplier:
Adipogen
Description:
Building block for synthesis.
Supplier:
Thermo Scientific Chemicals
Description:
100ml CAS: 2622-05-1, MDL: MFCD00000473
Catalog Number:
(76842-298)
Supplier:
AMBEED, INC
Description:
Trityl chloride 98%
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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