(3-Chloro-5-methylphenyl)cyclopropylmethanone
Catalog Number:
(10334-050)
Supplier:
Bioss
Description:
Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis. ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1.
Catalog Number:
(97061-350)
Supplier:
VWR
Description:
Suited for purification of nucleic acids or polypeptides from cell sources and inhibition of both RNase and protease activity.
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
pH adjusters are used to adjust the pH of formulations. This category includes acids that are notoriously difficult to source as truly cGMP-produced and amino acids that most companies do not fully test for EP, BP and JP. Avantor provides all that and more with our cGMP-produced acids and mutli-compendial amino acids.
Catalog Number:
(103650-178)
Supplier:
Sino Biological
Description:
Produced in rabbits immunized with purified, recombinant Human BLNK / Ly-57 / SLP-65 (rh BLNK / Ly-57 / SLP-65; Catalog#12706-H07H; AAH18906.1; Met 1-Ser 456). BLNK / Ly-57 / SLP-65 specific IgG was purified by Human BLNK / Ly-57 / SLP-65 affinity chromatography.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
L(+)-Histidine monohydrochloride monohydrate 98%
Catalog Number:
(75791-414)
Supplier:
Prosci
Description:
KLKB1 is a 638 amino acids protein that belongs to the peptidase S1 family and plasma kallikrein subfamily. It contains a peptidase S1 domain and four apple domains. The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. It participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation.Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.
Catalog Number:
(103649-518)
Supplier:
Sino Biological
Description:
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human HGF / Hepatocyte Growth Factor (rh HGF / Hepatocyte Growth Factor; Catalog#10463-H08H; NP_000592.3; Met 1-Ser 728). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Catalog Number:
(89142-874)
Supplier:
Enzo Life Sciences
Description:
Potent inhibitor of endothelial and inducible nitric oxide synthase (eNOS/NOS III and iNOS/NOS II).
Supplier:
AMBEED, INC
Description:
tert-Butyl 1,8-diazaspiro[4.5]decane-8-carboxylate hcl, Purity: 95%, CAS Number: 1890715-57-7, Appearance: Solid, Storage: Inert atmosphere, 2-8C, Size: 1G
Catalog Number:
(10391-448)
Supplier:
Bioss
Description:
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq].
Supplier:
Bachem Americas
Description:
Kemptide, LRRASLG, is a synthetic peptide substrate corresponding to part of the phosphorylation site sequence in porcine liver pyruvate kinase. Kemptide is phosphorylated in vitro and in vivo by cAMP-dependent protein kinase and in vitro by protein kinase C.
Supplier:
BeanTown Chemical
Description:
CAS: 7647-01-0; EC No: 231-595-7; MDL No: MFCD00011324
UN No: UN1789; Haz Class: 8; Packing Group: II
Liquid; Molecular Formula: HCl; MW: 36.46
Catalog Number:
(10294-294)
Supplier:
Bioss
Description:
Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity).
Catalog Number:
(10801-894)
Supplier:
Rockland Immunochemical
Description:
ARAF belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. ARAF play a critical role in cell growth and development (1).The N-terminal regulatory domain of ARAF interacted with the putative mitochondrial proteins TOM and TIM44. ARAF is expressed predominantly in urogenital tissues (2). The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus. ARAF Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, and Cancer research.
Supplier:
BeanTown Chemical
Description:
CAS: 7647-01-0; EC No: 231-595-7; MDL No: MFCD00011324; RTECS: MW4025000
UN No: UN1789; Haz Class: 8; Packing Group: II
Liquid; Molecular Formula: HCl ; MW: 36.46
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