Text Search >
H-DAB(boc)-OH
Print…
You Searched For:
26,129 results were found
H-DAB(boc)-OH
Catalog Number:
(10247-298)
Supplier:
Bioss
Description:
Adapter protein that functions as clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and cargos containg non-phosphorylated NPXY internalization motifs, such as the LDL receptor, to recruit them to clathrin-coated pits. Can function in clathrin-mediated endocytosis independently of the AP-2 complex. Involved in endocytosis of integrin beta-1; this function seems to redundant with the AP-2 complex and seems to require DAB2 binding to endocytosis accessory EH domain-containing proteins such as EPS15, EPS15L1 and ITSN1. Involved in endocytosis of cystic fibrosis transmembrane conductance regulator/CFTR. Involved in endocytosis of megalin/LRP2 lipoprotein receptor during embryonal development. Required for recycling of the TGF-beta receptor. Involved in CFTR trafficking to the late endosome. Involved in several receptor-mediated signaling pathways. Involved in TGF-beta receptor signaling and facilitates phosphorylation of the signal transducer SMAD2. Mediates TFG-beta-stimulated JNK activation. May inhibit the canoniocal Wnt/beta-catenin signaling pathway by stabilizing the beta-catenin destruction complex through a competing association with axin preventing its dephosphorylation through protein phosphatase 1 (PP1). Sequesters LRP6 towards clathrin-mediated endocytosis, leading to inhibition of Wnt/beta-catenin signaling. May activate non-canonical Wnt signaling.
Catalog Number:
(10247-294)
Supplier:
Bioss
Description:
Adapter protein that functions as clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and cargos containg non-phosphorylated NPXY internalization motifs, such as the LDL receptor, to recruit them to clathrin-coated pits. Can function in clathrin-mediated endocytosis independently of the AP-2 complex. Involved in endocytosis of integrin beta-1; this function seems to redundant with the AP-2 complex and seems to require DAB2 binding to endocytosis accessory EH domain-containing proteins such as EPS15, EPS15L1 and ITSN1. Involved in endocytosis of cystic fibrosis transmembrane conductance regulator/CFTR. Involved in endocytosis of megalin/LRP2 lipoprotein receptor during embryonal development. Required for recycling of the TGF-beta receptor. Involved in CFTR trafficking to the late endosome. Involved in several receptor-mediated signaling pathways. Involved in TGF-beta receptor signaling and facilitates phosphorylation of the signal transducer SMAD2. Mediates TFG-beta-stimulated JNK activation. May inhibit the canoniocal Wnt/beta-catenin signaling pathway by stabilizing the beta-catenin destruction complex through a competing association with axin preventing its dephosphorylation through protein phosphatase 1 (PP1). Sequesters LRP6 towards clathrin-mediated endocytosis, leading to inhibition of Wnt/beta-catenin signaling. May activate non-canonical Wnt signaling.
Supplier:
AMBEED, INC
Description:
Boc-(S)-3-amino-4-(4-trifluoromethylphenyl)butyric acid ≥98%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 042205-250MG , MDL Number: MFCD01076283
Supplier:
AMBEED, INC
Description:
(S)-1-Boc-piperidine-3-carboxylic acid 97%
Catalog Number:
(EM1.05995.9025)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041875-1G , MDL Number: MFCD00797557
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 042390-1G , MDL Number: MFCD02179172
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041829-5G , MDL Number: MFCD01862942
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 042254-250MG , MDL Number: MFCD01861067
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 042244-250MG , MDL Number: MFCD01861064
Supplier:
AMBEED, INC
Description:
1-(tert-Butoxycarbonyl)piperidine-2-carboxylic acid 96%
Supplier:
AMBEED, INC
Description:
2-Methylpyrrolidine-1,2-dicarboxylic acid-1-tert-butyl ester 98%
Supplier:
APOLLO SCIENTIFIC
Description:
1-(tert-Butoxycarbonyl)piperidine-2-carboxylic acid
Supplier:
Bachem Americas
Description:
High affinity ligand for all five somatostatin receptors (sst1-sst5). In AtT-20 mouse anterior pituitary tumor cells which mainly express sst2 and sst5 receptors the binding affinity of this somatostatin analog was found to be higher than that of somatostatin-14 (H-1490) and octreotide (H-5972). In a model of epileptogenesis, however, KE 108 did not exhibit antiepileptic activity suggesting that the high potency and efficacy of a synthetic ligand to all known somatostatin receptors may not reproduce entirely the effects of the natural ligand.
Supplier:
AMBEED, INC
Description:
(S)-3-((tert-Butoxycarbonyl)amino)-3-(4-cyanophenyl)propanoic acid, Purity: 98%, CAS number: 500770-82-1, Appearance: Solid, Storage: Sealed in dry, Room Temperature, Size: 1G
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
|
|||||||||
List View
