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H-d-Ser(tBu)-OMe·HCl
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H-d-Ser(tBu)-OMe·HCl
Supplier:
AMBEED, INC
Description:
4-Nitrobenzylamine hydrochloride 97%
Catalog Number:
(80058-662)
Supplier:
MilliporeSigma
Description:
Polyamine that plays an important role in the regulation of cellular proliferation and differentiation. Inhibits neuronal nitric oxide synthase.
Supplier:
ALADDIN SCIENTIFIC
Description:
ATC 0175 hydrochloride ≥98% (by HPLC)
Supplier:
BeanTown Chemical
Description:
CAS: 13433-00-6; EC No: 236-556-8; MDL No: MFCD00012510
Crystalline; Molecular Formula: C7H13NO4·HCl; MW: 211.65
Melting Point: 165-170° (decomposes)
Hygroscopic
Supplier:
Thermo Scientific Chemicals
Description:
Molecular Formula: Pd in 20% HCl
Physical Form: Liquid Odor: Characteristic UN No.: 1789 MDL No.: MFCD03613603
Catalog Number:
(AAH64546-03)
Supplier:
Thermo Scientific Chemicals
Description:
3-(Aminomethyl) benzoic acid hydrochloride, Purity: 95%, CAS Number: 876-03-9, Molecular Formula: C8H9NO2.HCl, Color: White, Form: Powder, 1G
Supplier:
ALADDIN SCIENTIFIC
Description:
Product Application:R)-2-Aminobutyramide Hydrochloride is used as a reagent in the synthesis of a new class of 2-[(arylalkyl)amino]alkanamide derivatives which have anticonvulsant activity.
Catalog Number:
(10352-084)
Supplier:
Bioss
Description:
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Aurora B is a mitotic protein kinase that phosphorylates histone H3 (probably on Serine 10), behaves as a chromosomal passenger protein, and may regulate several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis. It localizes to the inner centromere region from prophase to anaphase. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
Catalog Number:
(10326-624)
Supplier:
Bioss
Description:
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC, and to a lesser degree VEGFA, thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by forming heterodimers. The secreted isoform 3 may function as a decoy receptor for VEGFC and/or VEGFD and play an important role as a negative regulator of VEGFC-mediated lymphangiogenesis and angiogenesis. Binding of vascular growth factors to isoform 1 or isoform 2 leads to the activation of several signaling cascades; isoform 2 seems to be less efficient in signal transduction, because it has a truncated C-terminus and therefore lacks several phosphorylation sites. Mediates activation of the MAPK1/ERK2, MAPK3/ERK1 signaling pathway, of MAPK8 and the JUN signaling pathway, and of the AKT1 signaling pathway. Phosphorylates SHC1. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Promotes phosphorylation of MAPK8 at 'Thr-183' and 'Tyr-185', and of AKT1 at 'Ser-473'.
Catalog Number:
(TCT2379-25G)
Supplier:
TCI America
Description:
CAS Number: 42221-52-3
Molecular Formula: C7HCl5O
Molecular Weight: 278.33
Purity/Analysis Method: <gt/>98.0% (GC,T)
Form: Crystal
Color: White
Melting point (°C): 40
Supplier:
TCI America
Description:
n-Octylamine Hydrochloride, Purity: >98.0%(T), CAS Number: 142-95-0, Molecular Formula: C8H19N.HCl, Molecular Weight: 165.71, Synonyms: OACl, n-Octylammonium Chloride, Size: 5G
Catalog Number:
(10799-934)
Supplier:
Rockland Immunochemical
Description:
AKT2 Antibody detects AKT2 which is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as Protein Kinase B (PKB) and rac (related to A and C kinases). AKT is a key regulator of many signal transduction pathways. AKT Exhibits tight control over cell proliferation and cell viability. Overexpression or inappropriate activation of AKT is noted in many types of cancer. AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3-kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis; (ii) promotion of proliferation. Anti-AKT2 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Supplier:
Spectrum Chemicals
Description:
1-Benzyl-1-phenylhydrazine Hydrochloride, purity: 98.0 %, CAS number: 5705-15-7, Molecular Formula: C13H14N2.HCl, Molecular weight: 234.73, Color: White, Pale Yellow, Form: Solid, synonyms: alpha-Benzyl-alpha-phenylhydrazine hydrochloride, size: 25 g
Supplier:
AMBEED, INC
Description:
rel-4-((2R,6S)-2,6-Dimethylpiperidin-1-yl)-1-phenyl-1-(pyridin-2-yl)butan-1-ol hydrochloride ≥98%
Catalog Number:
(10261-356)
Supplier:
Bioss
Description:
SCA11 is a 1,244 amino acid protein that belongs to the protein kinase superfamily and the CK1 Ser/Thr protein kinase family. The SCA11 gene, comprising of 16 exons, produces a 5.6-kb transcript in which the longest open reading frame is 3,732 nucleotides. Defects in the SCA11 protein are the cause of the disorder spinocerebellar ataxia type 11 (SCA11). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. The SCA11 disorder is an autosomal dominant cerebellar ataxia (ADCA). It is a relatively benign, late-onset, slowly progressive neurologic disorder. The SCA11 protein has also been implicated in Alzheimer disease and in tangle formation. Existing as three alternatively spliced isoforms, the SCA11 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 15q15.2.
Catalog Number:
(10261-098)
Supplier:
Bioss
Description:
SCA11 is a 1,244 amino acid protein that belongs to the protein kinase superfamily and the CK1 Ser/Thr protein kinase family. The SCA11 gene, comprising of 16 exons, produces a 5.6-kb transcript in which the longest open reading frame is 3,732 nucleotides. Defects in the SCA11 protein are the cause of the disorder spinocerebellar ataxia type 11 (SCA11). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. The SCA11 disorder is an autosomal dominant cerebellar ataxia (ADCA). It is a relatively benign, late-onset, slowly progressive neurologic disorder. The SCA11 protein has also been implicated in Alzheimer disease and in tangle formation. Existing as three alternatively spliced isoforms, the SCA11 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 15q15.2.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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