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4-(Trifluoromethylthio)benzaldehyde
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4-(Trifluoromethylthio)benzaldehyde
Supplier:
AMBEED, INC
Description:
GDC0994 ≥98%
Supplier:
Adipogen
Description:
MK-2461 is a novel ATP-competitive multitargeted inhibitor of activated c-Met kinases (N1100Y, Y1230C, Y1230H, Y1235D, and M1250T) with IC(50) values of 0.4 to 2.5nM.
Supplier:
ALADDIN SCIENTIFIC
Description:
AZD1480 has been used as an inhibitor of janus kinase 2 (JAK2) and signal transducer and activator of transcription 3 (STAT3) in an in vitro cell model of upper gastrointestinal adenocarcinoma. It has also been used in combination with bortezomib to study tumor-associated macrophage-mediated survival of myeloma cells.
Supplier:
ALADDIN SCIENTIFIC
Description:
A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively。
Supplier:
Enzo Life Sciences
Description:
Potent inhibitor of GSK-3 ATP-binding site.
Supplier:
Adipogen
Description:
Reversible cell permeable p300/CBP histone acetyltransferase (HAT) inhibitor. Specific inhibition to p300 (86%) compared to N-acetyltransferase, PCAF, GCN5, Rtt109, Sas or MOZ histone acetyltransferases (<lt/>10%). Cell growth inhibitor in melanoma and non-small-cell-lung (NSCL) human cancer cell lines.
Supplier:
Adipogen
Description:
JNJ38877605 is an orally bio-available, small-molecule, c-MET tyrosine kinase inhibitor with potential anti-neoplastic activity. It is potent (c-MET enzyme and Phospho-MET IC(50) values of 4nM and 50nM, respectively) and highly specific (selective over 229 other kinases tested).
Supplier:
Adipogen
Description:
GDC-0032 is a potent, next-generation beta isoform-sparing PI3K inhibitor targeting PI3Kalpha/delta/gamma with Ki of 0.29nM/0.12nM/0.97nM, <gt/>10 fold selective over PI3Kbeta.
Supplier:
Adipogen
Description:
LY2784544 is a potent JAK2 inhibitor with IC(50) of 3nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
Supplier:
Adipogen
Description:
AMG-1 is a potent inhibitor of human c-Met and RON with IC(50) values of 4 and 9nM respectively.
Supplier:
Adipogen
Description:
SCH900776 is a selective Chk1 inhibitor with an IC(50) of 3nM. It shows 50-fold selectivity for Chk1 versus Chk2.
Supplier:
ALADDIN SCIENTIFIC
Description:
Product Describtion:AMG-458 is a potent, selective and orally bioavailable c-Met inhibitor, with Ki values of 1.2 nM and 2.0 nM for human and mouse c-Met, respectively.
Supplier:
Adipogen
Description:
XL765 is active against class I PI3K (IC(50) = 39, 113, 9 and 43nM for p110alpha, beta, gamma and delta, respectively). XL765 also inhibits DNA-PK (IC(50) = 150nM) and mTOR (IC(50) = 157nM)
Supplier:
Adipogen
Description:
SGX523 is an ATP-competitive, triazolopyridazine-based inhibitor of MET at an IC(50) of 4nM. SGX523 has higher affinity for the unphosphorylated form of MET (Ki = 2.7nM) than the more active phospho-enzyme (Ki = 23nM). In a broad panel of 213 kinases, SGX523 was extremely selective, with no inhibition >36%, suggesting IC(50) values > 1µM, including the closely-associated RON kinase.
Supplier:
Adipogen
Description:
AMG-458 is a potent inhibitor of c-Met with an IC(50) of 60nM and displays selectivity against VEGFR2.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
tert-Butyl (((tert-butoxycarbonyl)amino)(1H-pyrazol-1-yl)methylene)carbamate 98%
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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