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SAFE AND SURE NEDERLAND B.V.
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SAFE AND SURE NEDERLAND B.V.
Catalog Number:
(95053-636)
Supplier:
Enzo Life Sciences
Description:
Thrombospondin 1 (TSP1) is a multidomain, multifunctional glycoprotein from platelets and certain vascular cells which is known to play an important role in cell-cell and cell-matrix interactions. TSP1 is a calcium-sensitive, disulfide-bonded trimer with a subunit molecular mass of 150kDa. TSP1 exists in different conformational states depending on the calcium ion concentration used in the purification buffers.
Supplier:
Enzo Life Sciences
Description:
Used in Western blot with species reactivity to Recognizes proteins containing the KDEL sequence in mammals, birds, insects and Plant.
Catalog Number:
(76284-974)
Supplier:
Enzo Life Sciences
Description:
Recombinant monclonal antibody (Mouse IgG1κ).
Recommended Applications: Flow Cytometry, IF, IHC, IP, FUNC
Catalog Number:
(76201-870)
Supplier:
Enzo Life Sciences
Description:
Recombinant monoclonal antibody
Catalog Number:
(10033-592)
Supplier:
Enzo Life Sciences
Description:
Designed to screen MMP-2 inhibitors using a quenched fluorogenic peptide.
Supplier:
Enzo Life Sciences
Description:
HPV type 16/18/31/33/51 probe can be optimized for use with polymer detection system or as optimized RTU with Enzo's streptavidin detection methods.
Catalog Number:
(76003-196)
Supplier:
Enzo Life Sciences
Description:
Potent inhibitor of VEGFR-2, MET, Kit and FLT3-ITD
Supplier:
Enzo Life Sciences
Description:
Highly selective and potent inhibitor against both mTORC1 and mTORC2.
Catalog Number:
(10050-180)
Supplier:
Enzo Life Sciences
Description:
Grp78 (Glucose Regulated 78kDa Protein), is also known as BiP or Immunoglobulin heavy chain binding protein. It is a stressresponse protein which is induced by agents or conditions that adversely affect endoplasmic reticulum (ER) function. This protein is essential for the proper glycosylation, folding, and assembly of many membrane bound and secreted proteins as well as for maintenance of cell homeostasis and the prevention of apoptosis.
Catalog Number:
(10049-394)
Supplier:
Enzo Life Sciences
Description:
Polyclonal Antibody, Primary Antibody, Used in WB with species reactivity to Human, Mouse, Rat, Dog, Monkey, clam, Guinea pig, horse, Rabbit, Host: Rabbit, Immunogen: Synthetic peptide corresponding to the sequence near the N-terminus of human BTK
Catalog Number:
(10049-806)
Supplier:
Enzo Life Sciences
Description:
Cytochrome c, which is a critical component of the electron transport chain, is a component of the functional apoptosome. Upon release from the mitochondria, cytochrome c binds to the adaptor proteins Apaf-1 and procaspase-9 to form a cytosolic apoptosome complex. This event results in activation of procaspase-9 and its subsequent cleavage and activation of caspase-3 leading to the degradation of a series of cellular substrates and subsequently cell death.
Catalog Number:
(10049-744)
Supplier:
Enzo Life Sciences
Description:
The actions of the octapeptide circulatory hormone angiotensin II are mediated by type one (AT1) and type two (AT2) angiotensin II receptors, members of the seven-transmembrane domain-containing GPCR family. AT1 expression is greatest in vascular smooth muscle, liver, kidney, adrenal cortex, brain, and lung, and is primarily responsible for the physiological effects of angiotensin II in cardiovascular homeostasis. The AT2 receptor displays approximately 30% identity to the AT1 receptor, and is highly expressed during embryonic development. AT2 expression in adult tissue is limited to the adrenal medulla, brain, and reproductive tissues, but is upregulated in injured tissue following myocardial infarction, vascular injury, and wound healing.
Catalog Number:
(10049-542)
Supplier:
Enzo Life Sciences
Description:
The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress. It includes cytoplasmic (Hsp90-alpha/beta), ER (Grp94) and mitochondrial (TRAP1) localized members. Hsp90 is structurally composed of an N-terminal ATP binding domain, a medial substrate-binding region, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones to stabilize a multitude of client protein substrates. TRAP1 (aka Hsp75) was originally identified as a chaperone binding partner for retinoblastoma protein. TRAP1 was later found by immunofluorescence to be localized to the mitochondria. TRAP1 is significantly more active as an ATPase due in part to the lack of regulatory elements in the C-terminus, but retains the ability to dimerize. However, it does not form stable complexes with typical cochaperones of Hsp90 like p23 and HOP4. Recently TRAP1 has been identified as a protective element for cell survival, and has been suggested as a novel target for anti-cancer therapeutics.
Catalog Number:
(10050-176)
Supplier:
Enzo Life Sciences
Description:
Grp78 (Glucose Regulated 78kDa Protein), is also known as BiP or Immunoglobulin heavy chain binding protein. It is a stressresponse protein which is induced by agents or conditions that adversely affect endoplasmic reticulum (ER) function. This protein is essential for the proper glycosylation, folding, and assembly of many membrane bound and secreted proteins as well as for maintenance of cell homeostasis and the prevention of apoptosis.
Catalog Number:
(10049-484)
Supplier:
Enzo Life Sciences
Description:
Chaperonin 10 (Cpn10 or Hsp10), is the ~10 kDa mammalian equivalent to GroES of E. coli. Chaperonins play fundamental roles in the folding, assembly, and translocation of other proteins. Chaperonin 10 has been located in human platelets but more importantly it may also be present in human maternal serum. It has been reported that human Cpn10 is identical with Early pregnancy factor (EPF), which is involved in control over cell growth and development.
Catalog Number:
(10050-318)
Supplier:
Enzo Life Sciences
Description:
Adrenergic receptors mediate the hormone and neurotransmitter functions of adrenaline and noradrenaline. Adrenoreceptors function in peripheral tissues and the central nervous system to regulate numerous vascular, metabolic, and neurological functions, and are the target for many therapeutically relevant drugs including those for the treatment of hypertension, asthma, benign prostatic hypertrophy, and depression. Adrenoreceptors are classified by three types and multiple subclasses (alpha1A,1B,1D; alpha2A,2B,2C; and beta1,2,3) based on pharmacological and molecular characteristics.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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