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Van Der Voort Lucht en Milieu Amste
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Van Der Voort Lucht en Milieu Amste
Supplier:
Adipogen
Description:
SB203580 is a specific, ATP competitive, cell-permeable inhibitor of p38 MAPK with IC(50) of 0.3-0.5µM. It is 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and blocks PKB phosphorylation with IC(50) of 3-5µM.
Catalog Number:
(102988-962)
Supplier:
Adipogen
Description:
Setomimycin is a 9,9`-Bianthryl polyketide derivative.
Catalog Number:
(102511-914)
Supplier:
Adipogen
Description:
Human CD4 is a cell surface glycoprotein of 55kDa expressed on most thymocytes, on about two thirds of peripheral T cells and on some monocyte macrophage lineage cells. CD4 interacts with MHC Class II molecules in an accessory role during foreign antigen recognition by T cells. The extracellular portion of CD4 is an array of four Ig-like domains. The N-terminal region of CD4 is a receptor for the HIV-1 viral protein gp120.
Supplier:
Adipogen
Description:
Florescent probe that is commonly used as a building block to synthesize coumarin-type fluorescent probes. Spectral data: lambdaex 320 nm, lambdaem 380 nm in methanol. It is used as a fluorescent label for peptides. It is widely used for developing FRET peptide substrates for analyzing protease activities and for HPLC derivatization by fluorescence detection.
Catalog Number:
(102512-696)
Supplier:
Adipogen
Description:
The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE.
Catalog Number:
(102512-980)
Supplier:
Adipogen
Description:
Human CD106 is an endothelial adhesion molecule that binds to alpha 4 beta 1 and alpha 4 beta 7 integrins (VLA-4) and promotes adhesion of lymphocytes, monocytes, eosinophils and basophils. CD106 is also found on follicular dendritic cells, interdigitating recticulum cells and Kupffer cells.
Catalog Number:
(102512-930)
Supplier:
Adipogen
Description:
Human CD95 (APO-1; Fas) is a type I cell surface glycoprotein that is strongly upregulated on activated T cells, B cells, NK cells and thymocytes. CD95 plays an important role in programmed cell death or apoptosis. Apoptosis appears to be a mechanism for regulating the immune response.
Supplier:
Adipogen
Description:
Building block for synthesis.
Supplier:
Adipogen
Description:
Reference standard.
Supplier:
Adipogen
Description:
Fluorescent probe and pH indicator. It fluoresces blue in acidic solutions and in acidic organelles but fluoresces green in more basic organelles. This compound is potentially useful as a coloring agent, biological stain or optical detecting reagent. It is used in water-in-oil-in-water emulsions and as a substrate for lipase activity. Spectral data: lambdaex 375nm, lambdaem 404nm in water.
Supplier:
Adipogen
Description:
Derivative of Aphidicolin (BVT-0307) http://www.adipogen.com/bvt-0307/-aphidicolin.html. Mycotoxin. So far no comparison to aphidicolin's biological activity (DNA polymerase alpha antiviral and antitumor activity) has been performed.
Catalog Number:
(102513-016)
Supplier:
Adipogen
Description:
Human CD44 molecules appear to serve as lymphocyte adhesion molecules with numerous functions in extracellular matrix binding, cell migration, hemopoisis and lymphocyte homing.
Supplier:
Adipogen
Description:
Selective protein kinase C (PKC) inhibitor. Inhibits proliferation of cultured mouse epidermal keratinocytes. Enhances Fas- and TRAIL-mediated apoptosis. Inhibits T cell-mediated autoimmune diseases. Inhibits stimulation of insulin secretion by glucose. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2).
Catalog Number:
(102512-874)
Supplier:
Adipogen
Description:
Human CD81 is a member of the tetraspan family of leukocyte cell surface molecules which are involved in signal transduction, cell-cell adhesion and cellular activation. Association of CD81 with integrins appears to be functionally important in the regulation of cell adhesion and activation. Recent work with CD81-null mice indicates CD81 is important for development of humoral immune response.
Catalog Number:
(102513-258)
Supplier:
Adipogen
Description:
Human CD86 (B7-2) is a costimulating ligand for CD28 and CD152 (CTLA-4). CD86 is expressed on activated B cells and blood monocytes.
Catalog Number:
(102514-710)
Supplier:
Adipogen
Description:
Negative control in experiments with recombinant proteins fused to human IgG1 Fc.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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