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Van Der Voort Lucht en Milieu Amste
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Van Der Voort Lucht en Milieu Amste
Catalog Number:
(102512-834)
Supplier:
Adipogen
Description:
Immunoglobulin expressed by the mouse plasmacytoma TEPC 183 is an IgMkappa isotype of unknown binding specificity. It is used as a negative control when working with human cells.
Supplier:
Adipogen
Description:
Antiprion agent. Inhibitor of protein aggregation. Specifically reduces accumulation of a pathogenic fragment of Huntingtin in a transiently transfected cellular model of Huntington’s disease (HD). Tool for treating HD and other polyglutamine expansion associated diseases.
Catalog Number:
(102513-264)
Supplier:
Adipogen
Description:
Human CD80 (B7-1) is a costimulatory ligand for CD28 and CD152 (CTLA-4). CD80 is expressed on activated B cells.
Catalog Number:
(102512-036)
Supplier:
Adipogen
Description:
Human CD13 is a zinc-binding aminopeptidase-N enzyme expressed on the surface of myeloid cells. IL-4 will upregulate expression of CD13 which may play an anti-inflammatory role.
Catalog Number:
(102511-764)
Supplier:
Adipogen
Description:
Human MHC Class I (HLA-A, B & C) molecules are expressed on nearly all nucleated cells. MHC Class I molecules consist of heterodimers of a highly polymorphic transmembrane alpha chain and an invariant beta chain. MHC Class I molecules bind to endogenously synthesized peptides of about 8-10 amino acids which are presented to CD8+ T cells. Evidence indicates exogenously derived peptides are also presented by MHC Class I molecules.
Catalog Number:
(102512-182)
Supplier:
Adipogen
Description:
Human CD27 is a lymphocyte specific member of the TNF receptor family and is found primarily on peripheral blood T cells and on a subpopulation of B cells and NK cells. The ligand for CD27 is CD70, which is a member of the TNF ligand superfamily.
Catalog Number:
(102513-502)
Supplier:
Adipogen
Description:
Bafilomycin C1 is a potential anti-osteoporotic agent in treating bone lytic diseases.
Catalog Number:
(102514-332)
Supplier:
Adipogen
Description:
Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.
Supplier:
Adipogen
Description:
N-Dodecanoyl-L-homoserine lactone (C12-HSL) is a small diffusible signalling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. In addition to regulating bacterial functions, C12-HSL activates NF-kappaB in RAW 264.7 macrophages, increasing the expression of TNF-alpha, interleukin-1beta (IL-1beta) and IL-8, while other lactones do not. In addition, C12-HSL alters cell cycling and metabolism of human keratinocyte (HaCaT) cells. It is important to note that C12-HSL is distinct from N-3-oxo-dodecanoyl-L-homoserine lactone, which is produced at different times in biofilm development and has different cellular effects.
Supplier:
Adipogen
Description:
Fluorescent probe for binding to proteins etc. quantum yield increases by decreasing free rotation. Fluorescent molecular rotor.
Catalog Number:
(102511-828)
Supplier:
Adipogen
Description:
Human surface membrane bound IgM complexes with a heterodimer of transmembrane proteins of Igalpha and Igbeta (CD79a and CD79b) to form the B cell antigen receptor (BCR). The BCR complex plays an important role in B cell development and activation. The transmembrane region of mIgM is essential for functional BCR complex assembly.
Catalog Number:
(102512-858)
Supplier:
Adipogen
Description:
Human CD79b is the B cell antigen receptor Ig beta chain (BCR-Ig beta) which associates with B cell antigen receptor Ig alpha chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg) (3). The mIgM component binds antigen and the Ig alpha/Ig beta heterodimer transduces signals. Analysis of CD79b expression is useful in diagnosis of B cell lymphoproliferative disorders.
Catalog Number:
(102512-348)
Supplier:
Adipogen
Description:
Human CD44 molecules appear to serve as lymphocyte adhesion molecules with numerous functions in extracellular matrix binding, cell migration, hemopoisis and lymphocyte homing.
Catalog Number:
(102988-736)
Supplier:
Adipogen
Description:
Cell permeable compound capable of slowing anaphase-promoting complex/cyclosome (APC/C)-dependent proteolysis. Inhibitor of the ubiquitin ligase activity of the APC/C by inhibiting substrate binding to Cdc20. Distinct mechanism of action than proTAME. Blocks mitotic exit only modestly when used alone in cultured cells. A strong synergistic effect is observed when Apcin and proTAME are used simultaneously, providing a more robust mitotic arrest. This may be very beneficial when treating cells that do not efficiently convert proTAME to its active parent compound (TAME) or if experiments demand strong APC/C inhibition.
Catalog Number:
(102512-290)
Supplier:
Adipogen
Description:
Human CD38 is a type II transmembrane glycoprotein with bifunctional ectoenzyme activity catalyzing both synthesis and hydrolysis of cyclic ADP ribose. CD38 is involved in lymphocyte activation and adhesion to endothelium and has been identified as a counter-receptor of CD31.
Catalog Number:
(102514-444)
Supplier:
Adipogen
Description:
Nampt also known as pre-B cell colony-enhancing factor 1 (PBEF1) or visfatin is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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