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1-(But-3-yn-1-yl)piperazine
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1-(But-3-yn-1-yl)piperazine
Supplier:
AMBEED, INC
Description:
CTx-0294885 98%
Catalog Number:
(101822-670)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 026694-500MG , MDL Number: MFCD09997691
Supplier:
AMBEED, INC
Description:
5-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline, Purity: 98%, CAS Number: 1432597-26-6, Appearance: Form: solid, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 5mg
Supplier:
AMBEED, INC
Description:
1-Methyl-4-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine, Purity: 96%, CAS Number: 883738-27-0, Appearance: Solid or liquid, Storage: Sealed in dry, 2-8C, Size: 1G
Supplier:
AMBEED, INC
Description:
4-Piperazinylphenylboronic acid, pinacol ester 95%
Catalog Number:
(101809-110)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 019952-500MG , MDL Number: MFCD07801106
Supplier:
MilliporeSigma
Description:
Free acid for molecular biology. DNase-, RNase-, protease-, and phosphatase-free.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
HEPES sodium salt 99+% for molecular biology DNase-, RNase-, protease-free
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
HEPES-2-[4-(2-Hydroxyethyl)-1-piperazinyl]-ethanesulfonic acid 99% for biochemistry
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 053761-500MG , MDL Number: MFCD04116565
Supplier:
MP Biomedicals
Description:
HEPES is a zwitterionic organic chemical buffering agent; one of the twelve Good's buffers.
Supplier:
Adipogen
Description:
AV-412 is a potent dual inhibitor of EGFR and ErbB2 tyrosine kinases, including the mutant EGFR(L858R,T790M), which is clinically resistant to the EGFR-specific kinase inhibitors erlotinib and gefitinib. In enzyme assays assay the compound inhibited the EGFR variants and ErbB2 in the nanomolar range with over 100-fold selectivity compared with other kinases, apart from ABL and FLT1, which were both moderately sensitive to the compound. In cells, AV-412 inhibited autophosphorylation of EGFR and ErbB2 with IC(50) of 43 and 282 nM, respectively. It also inhibited epidermal growth factor (EGF)-dependent cell proliferation with an IC(50) of 100nM. Moreover, AV-412 abrogated EGFR signaling in the gefitinib-resistant H1975 cell line, which harbors a double mutation of L858R and T790M in EGFR. In animal studies using cancer xenograft models, AV-412 (30mg/kg) demonstrated complete inhibition of tumor growth of the A431 and BT-474 cell lines, which overexpress EGFR and ErbB2, respectively.
Catalog Number:
(101837-136)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 034178-500MG , MDL Number: MFCD06740639
Supplier:
AMBEED, INC
Description:
1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid sesquihydrate, Purity: 98%, CAS Number: 84294-96-2, Appearance: Form: Crystal - Powder, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 10g
Supplier:
AMBEED, INC
Description:
(R)-1-(4-((1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c][7]annulen-6-yl)piperazin-1-yl)-3-(quinolin-5-yloxy)propan-2-ol trihydrochloride, Purity: 98%, CAS number: 167465-36-3, Appearance: White to Yellow Solid, Storage: Inert atmosphere, Room Temperature, Size: 25MG
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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