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3,5-Difluoro-2-hydroxybenzonitrile
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3,5-Difluoro-2-hydroxybenzonitrile
Catalog Number:
(101788-354)
Supplier:
Matrix Scientific
Description:
MF=C7H4F2O MW=142.11 Cas=2646-90-4 MDL=MFCD00010327 100G
Supplier:
TCI America
Description:
CAS Number: 35730-09-7
MDL Number: MFCD00009929 Molecular Formula: C7H3ClF2O Molecular Weight: 176.55 Purity/Analysis Method: >98.0% (GC,T) Form: Clear Liquid Boiling point (°C): 93 Flash Point (°C): 59 Specific Gravity (20/20): 1.44
Supplier:
Thermo Scientific Chemicals
Description:
1g CAS: 119256-40-5, MDL: MFCD00276099
Supplier:
Adipogen
Description:
GSK2126458 is an orally available selective inhibitor of the class I phosphoinositide 3-kinase (PI3K) enzymesand MTOR1/2 complexes. GSK2126458 can inhibit PI3K-alpha (p85alpha/p110alpha) with IC(50) of 0.04nM. GSK2126458 has Ki values in the picomolar range for each of the class I PI3K isoforms and MTOR1/2 complexes. GSK2126458 has potent in vitro and in vivo growth-inhibitory effects on cancer cells. In comparison with other clinical PI3K inhibitors, GSK2126458 is around 100-fold more potent than BEZ235 (6nM). GSK2126458 also a low picomolar inhibitor of the common activating mutants of p110R ( E542K, E545K, and H1047R ) with Ki of 0.008nM, 0.008nM and 0.009nM in human cancer. In mechanistic cellular assays, GSK2126458 caused a significant reduction in the levels of pAKT-S473 with remarkable potency. Consistent with its activity against both PI3K R and mTOR, GSK2126458 also inhibits phosphorylation of AKT-T308 and p70S6K at low nanomolar concentrations. GSK2126458 induces a G1 cell cycle arrest and inhibits cell proliferation in a large panel of cell lines, including T47D and BT474 breast cancer lines.
Catalog Number:
(101788-442)
Supplier:
Matrix Scientific
Description:
MF=C7H4F2O2 MW=158.11 Cas=455-86-7 MDL=MFCD00011672 100G
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 007430-25G , MDL Number: MFCD00069118
Catalog Number:
(76485-546)
Supplier:
AAT BIOQUEST INC
Description:
Bodi Fluor™ 576/589 is chemically the same molecule to BODIPY™ 576/589 dye.
Supplier:
VWR International
Description:
Really versatile general purpose mid-polarity phase for a wide range of applications. Ideal in confirmation analysis.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 021128-5G , MDL Number: MFCD08061907
Supplier:
Matrix Scientific
Description:
MF=C6H3Clf2O MW=164.54 Cas=261762-51-0 MDL=MFCD01631330 1G
Supplier:
Matrix Scientific
Description:
MF=C7H3Clf2O MW=176.55 Cas=18355-73-2 MDL=MFCD00042499 5G
Catalog Number:
(101796-510)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 009153-5G , MDL Number: MFCD04038355
Supplier:
AMBEED, INC
Description:
Ethyl bromodifluoroacetate 98%
Supplier:
VWR International
Description:
General purpose column with added high temperature stability for the analysis of Pesticides, PCBs, substituted polar compounds, phenols, etc.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Ethyl bromodifluoroacetate 98%
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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