BMS-303141
Supplier:
AMBEED, INC
Description:
BMS-303141 98%
Catalog Number:
(101845-150)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 038265-500MG , MDL Number: MFCD01151497
Catalog Number:
(77620-874)
Supplier:
AMBEED, INC
Description:
BMS-8 98%
Supplier:
AMBEED, INC
Description:
Brivanib (BMS-540215) 96%
Supplier:
Adipogen
Description:
BMS-599626 is an orally bioavailable, highly selective and potent pan-HER kinase inhibitor. It inhibits HER1 and HER2 with IC(50) values of 20 and 30nM, respectively.
Supplier:
AMBEED, INC
Description:
BMS-708163 98+%
Supplier:
AMBEED, INC
Description:
BMS-582949 ≥98%
Supplier:
AMBEED, INC
Description:
BMS-599626 hydrochloride 98+%
Supplier:
Adipogen
Description:
BMS-540215 is an ATP-competitive inhibitor of human VEGFR-2, with an IC(50) of 25nM and Ki of 26nM. BMS-540215 also showed good selectivity for FGFR-1 (IC(50) of 48nM), FGFR-2 (IC(50) of 125nM), and FGFR-3 (IC(50) of 68nM).
Supplier:
Adipogen
Description:
BMS-2 is a potent MET kinase inhibitor with an IC(50) value of 1.8nM. It also possesses potent inhibitory activity against Flt-3 and VEGFR-2 kinases, IC(50) values of 4nM and 27nM respectively.
Supplier:
AMBEED, INC
Description:
BMS-777607 98%
Supplier:
Adipogen
Description:
BMS387032 is a novel cyclin-dependent kinase inhibitor, which exhibits potent and selective inhibitory activity against Cdk2, Cdk7, and Cdk9. It inhibits CDK2 with an IC(50) of 48nM and up to 20-fold selective over CDK1/CDK4. It also inhibits CDK7/9 with IC(50) values of 62nM and 4nM. It has little effect on CDK6.
Supplier:
AMBEED, INC
Description:
BMS-863233 hydrochloride ≥98%
Supplier:
Adipogen
Description:
Kinases, such as LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2), have been identified as participating in signal pathways affecting actin dynamics by deactivating cofilin. Over expression of LMK1 has been found in invasive breast and prostate cancer cell lines and suppression of LIMK 2 expression has been found to limit migration of human fibrosarcoma cells. Thus, the inhibition of LIMK1 and/or LIMK2 enzymes have been suggested as targets for treating cancer, including reduction or prevention of metastasis. BMS-5 is a potent inhibitor of the LIM kinase. It has IC(50) values of 7nM and 8nM for LIMK1 and LIMK2 respectively. LIMK1/2 activity was measured via TCA precipitation assay using a biotinylated ADF (actin depolymization factor) as the protein substrate and the kinase domains of LIMK1 and LIMK2 as the enzyme sources in the presence of 1µM ATP.
Supplier:
Adipogen
Description:
BMS-3 is a potent inhibitor of the LIM kinase. It has IC(50)'s of 5nM and 6nM for LIMK1 and LIMK2 respectively.
Supplier:
AMBEED, INC
Description:
BMS-626529 98%
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