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Supplier:
Diagnostic Biosystems
Description:
This antibody is specific to erythroid cells at various stages of differentiation from the erythroblast to the mature red cell.
Catalog Number:
(76634-316)
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with an antigen expressed by normal and neoplastic T cells and myeloid lineage cells. It strongly stains T cells in the interfollicular areas of normal lymphoid tissues.
Supplier:
Diagnostic Biosystems
Description:
This antibody stains with S-100 protein. S-100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S-100a and S-100b proteins are two members of the S-100 family. S-100a is composed of an α and β chain whereas S-100b is composed of two β chains. This antibody stains schwannomas, ependymomas, astrogliomas, almost all benign and malignant melanomas and their metastases.
Supplier:
Diagnostic Biosystems
Description:
Chromogranin A is a 439 amino acid protein present in secretory granules of a wide variety of endocrine cells and neurons. A positive staining is seen in the secretory granules of parathyroid, adrenal medulla, anterior pituitary gland and Langerhans islets of pancreas. This antibody stains a variety of neuroendocrine tumors.
Supplier:
Diagnostic Biosystems
Description:
This antibody is specific to CD74. This antibody can be used for the identification of B cell lymphomas and leukemias. It also stains activated neoplastic cells in T cell lymphomas and Sternberg-Reed cells.
Supplier:
Diagnostic Biosystems
Description:
MSH6 is a heterodimer of MSH2 and binds to DNA containing G/T mismatches. The MSH2-MSH6 complex recognizes a single-base mispair insertion/deletion loop. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. Studies have shown the mutations of MLH-1, MSH2 and MSH6 genes contribute to the development of sporadic colorectal carcinoma. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time.
Catalog Number:
(76634-612)
Supplier:
Diagnostic Biosystems
Description:
This antibody is specific against an epitope located on the β chain (i.e. in S-100a and S-100b) but not on the α chain of S-100 (i.e. in S-100a and S-100ao). This antibody can be used to localize S-100a and S-100b in various tissue sections.
Catalog Number:
(76635-216)
Supplier:
Diagnostic Biosystems
Description:
SITVue /DAB detection system is a powerful Intensification system that significantly enhances chromogenic signals. This system can be integrated into standard immunohistochemistry (IHC) staining methods.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with β-amyloid protein. This antibody stains amyloid plaques within the cortex, and amyloid deposits in blood vessels. β-amyloid deposits are also detected in Lewy body dementia, Down syndrome, amyloidosis and in Gram-Parkinson dementia complex. The presence of a large number of neuritic plaques (senile) and neurofibrillary tangles in the cerebral cortex is used as a pathological marker for a disease state and presents the major criterion for the diagnosis of Alzheimer’s disease at autopsy.
Supplier:
Diagnostic Biosystems
Description:
ERG, the ETS related gene, belongs to the ETS family that plays important roles in cell development, differentiation, proliferation, apoptosis and tissue remodeling. The ERG antibody identifies endothelial cells, lymphocytes and prostate cancer cells.
Catalog Number:
(95029-754)
Supplier:
Diagnostic Biosystems
Description:
Prediluted mouse monoclonal antibody, clone XM26&LL002. 6ml.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. Mast cells contain a number of preformed chemicals mediators such as histamine, chymase, carboxypeptidase, and proteolytic tryptase. Human mast cell chymase is considered to be an important marker of mast cells and is an important mediator of inflammation.
Supplier:
Diagnostic Biosystems
Description:
This antibody is specific to 50 kDa cytokeratin protein designated cytokeratin 14. Cytokeratin 14 belongs to the type A (acidic) subfamily of low molecular weight cytokeratins and exists in combination with cytokeratin 15. This antibody can be used to distinguish stratified epithelial cells from simple epithelial cells.
Catalog Number:
(76634-406)
Supplier:
Diagnostic Biosystems
Description:
The G168-15 antibody recognizes human and mouse MLH1 (80 to 85 kDa). The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC). MSH-2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process. It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.
Catalog Number:
(99991-136)
Supplier:
Diagnostic Biosystems
Description:
Clone number SP7. The CD3 antigen is present on early thymocytes and mature T cells and is generally regarded as a Pan T cell marker. This rabbit monoclonal antibody will help detect CD3 expression in normal and neoplastic tissues. This antibody reacts with the intracytoplasmic portion of the CD3 antigen expressed by T cells.
Supplier:
Diagnostic Biosystems
Description:
UnoVue Mouse AP Detection Reagent is a non-biotin one-step detection reagent suitable for demonstrating antigens in formalin-fixed paraffin-embedded tissues and frozen sections.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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