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H-d-Ser(tBu)-OMe·HCl
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H-d-Ser(tBu)-OMe·HCl
Catalog Number:
(76194-188)
Supplier:
Prosci
Description:
It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This mAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher's Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts.
Catalog Number:
(IC10247101)
Supplier:
MP Biomedicals
Description:
p-Nitrophenyl-alpha-D-galactopyranoside is used as a substrate for α-galactosidase.
Supplier:
AMBEED, INC
Description:
6,7-Dimethoxy-N-(2-methyl-4-phenoxyphenyl)quinazolin-4-amine hydrochloride, Purity: 98%, CAS Number: 2002381-31-7, Appearance: Off-white solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 25mg
Catalog Number:
(IC19069125)
Supplier:
MP Biomedicals
Description:
Guanine is one of the four main nucleobases found in the nucleic acids DNA and RNA. Guanine is a purine derivative.
Supplier:
Spectrum Chemicals
Description:
Betaine Hydrochloride is a vitamin-like substance that is found in many whole grains. It is an acidic form of betaine, which is a form of hydrochloric acid that is derived from the beet. It can be used as a supplement to aid in the digestion of proteins as well as other benefits. It is used as a moisturizer and stabilizer in skin care formulations and increases the water solubility of active compounds. In surfactant solutions, betaine acts as a foam modifier and increases the foam volume and stability and improves the after-feel of conditioners.
Catalog Number:
(IC10157825)
Supplier:
MP Biomedicals
Description:
L-3,4-Dihydroxyphenylalanine (L-DOPA), an anti-Parkinsonian agent, is the natural isomer of the immediate precursor to dopamine. L-DOPA is the product of the hydroxylation of L-tyrosine by tyrosine hydroxylase in brain and in adrenal medulla.
Supplier:
Thermo Scientific Chemicals
Description:
In pigments, galvanic batteries, lithography, weighting fabrics
Supplier:
Electron Microscopy Sciences
Description:
Reference: Elektronemikrokopische Swift, J.A. (1968). The electron histochemistry of cystine-containing proteins in thin transverse sections of human hair. J.R. Microsc. Soc. 88,449, Thiery, J.P. (1967). Mise en evidence des Polysaccharides sur coupes fines en microscopie eletronique. J. Microsc. (Paris) 6,987, Rambourg, A. (1967). An improved silver methenamine technique for the detection of periodic acid-reactive complex carbohydrates with the electron microscope.J. Histochem. Cytochem. 15, 409.
Catalog Number:
(75794-156)
Supplier:
Prosci
Description:
GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. It has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. It regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. GCN5 is a component of the Ada Two-A containing (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Supplier:
MP Biomedicals
Description:
Nisin is a polypeptide (34 residues) antibiotic structurally similar to subtilin but containing no tryptophan; a member of the lantibiotic family. Reduces the thermal resistance of bacterial spores in milk-based beverages.The C-terminus of nisin is responsible for the initial interaction of nisin, binding to the target membrane. Active against Gram-positive bacteria at the cytoplasmic membrane.
Supplier:
MP Biomedicals
Description:
Chlorpromazine Hydrochloride is a phenothiazine antipsychotic; a D2 and H1 antagonist. It inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase and is reported to uncouple and inhibit oxidative phosphorylation at 10-3 - 10-4 M. It is possibly a photogenotoxic agent in humans. Helps to induce hypothermia in mice in the dose range of 12.5 -100 mg/kg.
Chlorpromazine demonstrates cytotoxic and antiproliferative activity against leukemic cells, but does not affect the viability of normal lymphocytes. Phenothiazine antipsychotic; D2 dopamine receptor antagonist, H1 histamine receptor antagonist; inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase.
Catalog Number:
(TCP0599-100G)
Supplier:
TCI America
Description:
CAS Number: 569-61-9
MDL Number: MFCD00001657
Molecular Formula: C19H17N3
Molecular Weight: 323.82
Purity/Analysis Method: <gt/>95.0% (HPLC)
Form: Crystal
Melting point (°C): 270
Lambda max.: 539 nm (EtOH)
Catalog Number:
(75932-918)
Supplier:
Rockland Immunochemical
Description:
TINP1 (TGF-beta inducible nuclear protein 1), also known as NSA2 (Nop seven-associated 2), is a highly conserved nucleolar protein essential for large ribosomal subunit biogenesis. NSA2 is broadly expressed in human tissues and cultured cell lines, and located in the nucleolus of the cell. It is thought to be involved in cell proliferation and cell cycle regulation.
Catalog Number:
(75794-150)
Supplier:
Prosci
Description:
PARP-3 [ARTD3] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
Catalog Number:
(75929-670)
Supplier:
Rockland Immunochemical
Description:
LOXL3 is a member of the lysyl oxidase gene family. This family is essential to the biogenesis of connective tissue. The lysyl oxidase gene family encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin (1). LOXL3 is highly expressed in central nervous system, uterus, heart, and leukocyte (1). LOXL3 plays an important role in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis. LOXL3 Protein is ideal for investigators involved in Signaling Proteins, Lysyl Oxidase Proteins, Cancer, and Metabolic Disorder research.
Supplier:
Thermo Scientific Chemicals
Description:
Stripping tin coating from steel surfaces, in organic synthesis, as catalyst, in making other antimony salts, in chemical microscopy for drug identification
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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