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Potassium+hexacyanoferrate(III)
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Potassium+hexacyanoferrate(III)
Catalog Number:
(75843-148)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The A2F10 monoclonal antibody specifically reacts with mouse CD135, a tyrosine kinase class III receptor. CD135, also known as Flt3, Ly-72, and Flk-2, is the receptor for the FLT3 ligand (FLT3L) cytokine and is expressed on many hematopoietic progenitor cells. Signaling through CD135 plays a role in cell survival, proliferation, and differentiation. The A2F10 antibody is reported to inhibit the binding of FLT3L to CD135.
Catalog Number:
(10332-650)
Supplier:
Bioss
Description:
Matrix Metalloproteinase 8 (MMP8) is also known as neutrophil collagenase and collagenase 2. MMP8 degrades fibrillar collagens types I, II, III, aggrecan, serpins and alpha 2 macroglobulin. All collagenases cleave fibrillar collagens at one specific site resulting in generation of N terminal three quarter and C terminal one quarter fragments, which then denature to gelatin at body temperature. The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than type I or type II collagen, whereas MMP8 is more potent in degrading type I collagen than type III or type II collagen. MMP13, in turn degrades type II collagen 6 fold more efficiently than type I and type II collagens and displays almost 50 fold stronger gelatinolytic activity than MMP1 and MMP8. MMP8 is very similar to MMP1, sharing 57 % amino acid identity. Most cell types do not produce MMP8. Until recently, it was thought that MMP8 was produced exclusively by neutrophils, but it has also been detected in other cell types including arthritic chondrocytes and gingival fibroblasts. The human MMP8 gene has the chromosomal location of 11q22.2-22.3. MMP8 is heavily glycosylated, and the zymogen has a mass of 85 Kd. The zymogen is quickly activated to the 64 Kd form, and this breaks down to a cascade of active forms.
Catalog Number:
(10101-144)
Supplier:
Prosci
Description:
KCNK10 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is highly expressed in the kidney and pancreas. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. The protein is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Three transcript variants have been identified for this gene.
Catalog Number:
(10454-306)
Supplier:
Bioss
Description:
Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.
Catalog Number:
(10453-922)
Supplier:
Bioss
Description:
Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.
Catalog Number:
(76116-452)
Supplier:
Bioss
Description:
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
Catalog Number:
(MSPP-SEA176RA)
Supplier:
CLOUD-CLONE CORP MS
Description:
This assay has high sensitivity and excellent specificity for detecting Rat COL3 (Collagen Type III). The assay range is from 3.12 to 200 ng/ml (Sandwich kit) with a sensitivity of 1.17 ng/ml. There is no detectable cross to reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.
Catalog Number:
(MSPP-SEA176MU)
Supplier:
CLOUD-CLONE CORP MS
Description:
This assay has high sensitivity and excellent specificity for detecting Mouse COL3 (Collagen Type III). The assay range is from 2.4 to 150 ng/ml (Sandwich kit) with a sensitivity of 1.1 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.
Supplier:
BeanTown Chemical
Description:
CAS: 464-48-2; EC No: 207-354-7; MDL No: MFCD00064148; RTECS: EX1250000
UN No: UN2717; Haz Class: 4.1; Packing Group: III
Crystalline; Molecular Formula: C10H16O; MW: 152.24
Boiling Point: 204°; Flash point: 65°C (149°F)
Density (g/mL): 0.99; Optical Rotation: [α]20/D -43°, c = 10 in ethanol
Catalog Number:
(10453-260)
Supplier:
Bioss
Description:
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
Catalog Number:
(10453-274)
Supplier:
Bioss
Description:
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
Catalog Number:
(10453-280)
Supplier:
Bioss
Description:
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
Supplier:
BeanTown Chemical
Description:
CAS: 71-41-0; EC No: 200-752-1; MDL No: MFCD00002977; RTECS: SB9800000
UN No: UN1105; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: CH3(CH2)4OH; Molecular Formula: C5H12O ; MW: 88.15
Melting Point: -78°; Boiling Point: 136-138°; Flash point: 49°C (120°F)
Density (g/mL): 0.811; Refractive Index: 1.409
Supplier:
BeanTown Chemical
Description:
CAS: 141-43-5; EC No: 205-483-3; MDL No: MFCD00008183; RTECS: KJ5775000
UN No: UN2491; Haz Class: 8; Packing Group: III
Liquid; Linear Formula: HOCH2CH2NH2; Molecular Formula: C2H7NO; MW: 61.08
Melting Point: 10-11°; Boiling Point: 170°; Flash point: 86°C (187°F)
Density (g/mL): 1.012; Refractive Index: 1.454
Air Sensitive , Hygroscopic
Supplier:
BeanTown Chemical
Description:
CAS: 14649-03-7; EC No: 238-698-6; MDL No: MFCD00002036
UN No: UN2206; Haz Class: 6.1; Packing Group: III
Liquid; Molecular Formula: C9H9NO; MW: 147.17
Boiling Point: 55-56°/2.5 mmHg; Flash point: 65°C (149°F)
Density (g/mL): 1.045; Refractive Index: 1.515; Optical Rotation: [α]20/D -10°, neat
Moisture Sensitive
Catalog Number:
(10289-304)
Supplier:
Bioss
Description:
Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. DPP10 (dipeptidyl-peptidase 10), also known as DPRP3 (dipeptidyl peptidase IV-related protein 3), DPL2 or DPPY, is a non-functional dipeptidyl peptidase which can bind to the potassium channels KV4.1 and KV4.2. It is a single-pass type II membrane protein expressed in spinal cord, adrenal glands, pancreas and brain tissues and may act as a modulator for cell surface expression and activity of KV4.1 and KV4.2.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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