N-(2-Hydroxyethyl)methacrylamide
Supplier:
Enzo Life Sciences
Description:
A potent and selective, cell-permeable inhibitor of nitric oxide (NO)-sensitive soluble guanylyl cyclase (sGC). Inhibition is irreversible. Inhibits also the basal, the YC-1 and the coenhanced sGC activity. Complete inhibition of NO-induced relaxation in vascular and nonvascular smooth muscle at 1μM.
Supplier:
R&D Systems
Description:
Mouse CCR1 Fluorescein (Clone 643854), Host: Rat IgG2B, Monoclonal, Immunogen: E. coli-derived recombinant mouse CCR1. Extracellular regions (aa 1-34, aa 92-107, aa 172-192, aa 265-281), Host: Flow Cytometry, 100 Tests
Catalog Number:
(TCP0489-25ML)
Supplier:
TCI America
Description:
CAS Number: 75-33-2
MDL Number: MFCD00004863 Molecular Formula: C3H8S Molecular Weight: 76.16 Purity/Analysis Method: >96.0% (GC) Form: Clear Liquid Boiling point (°C): 53 Melting point (°C): -130 Flash Point (°C): -34 Specific Gravity (20/20): 0.82
Supplier:
TCI America
Description:
CAS Number: 10297-06-0
MDL Number: MFCD00013697 Molecular Formula: C6H9Cl Molecular Weight: 116.59 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 144 Flash Point (°C): 34 Specific Gravity (20/20): 0.96
Supplier:
Enzo Life Sciences
Description:
p53 inhibitor
Catalog Number:
(10476-820)
Supplier:
Bioss
Description:
The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC34 (coiled-coil domain containing 34), also known as Renal carcinoma antigen NY-REN-41, is a 373 amino acid protein that is expressed in testis, breast, lung, placenta, liver and small intestine. A translocation between the short arms of chromosomes 11 and 18 affecting the CCDC34 gene has been identified in a patient with hamartoma of the retinal pigment epithelium. There are two isoforms of CCDC34 that are produced as a result of alternative splicing events.
Supplier:
Dickies
Description:
Dickies® style LP600.
Supplier:
Remco Products
Description:
One-piece construction is effective in areas requiring the highest level of hygiene.
Catalog Number:
(102996-110)
Supplier:
Anaspec Inc
Description:
Gastrin-1 is also referred to as Gastrin-17 or “Little Gastrin.” Secretion of gastrin is induced by food intake and causes the release of gastric acid in the stomach. Secreted by the G cells in the gastric mucosa, it is one of the major bioactive forms of gastrin found in tissue and plasma (the other bioactive form is Gastrin-34 or Big Gastrin - Cat# AS-20747). Both Gastrin-17 and Gastrin-34 are carboxy-amidated and partially tyrosine sulfated. Binding of Gastrin to the CCK2/gastrin receptor requires carboxy-amidation, however sulfation is not necessary for binding to the receptor. Binding of Gastrin to the CCK2/Gastrin receptors on parietal cells of the stomach causes them to secrete hydrochloric acid (HCl) and stimulates lectin-like protein Reg expression via activation of PKC and RhoA. Gastrin also plays a role in release of Histamine and Pepsinogen.
Sequence: Pyr-GPWLEEEEEAYGWMDF-NH2 MW: 2098.2 Da % Peak area by HPLC: 95 Storage condition: -20° C
Supplier:
Spectrum Chemicals
Description:
Microcrystalline Cellulose, NF is an excipient in pharmaceutical formulations acting as a binder in tablet formation. All Spectrum Chemical NF grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
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Catalog Number:
(TCB1114-100ML)
Supplier:
TCI America
Description:
CAS Number: 917-92-0
MDL Number: MFCD00008852 Molecular Formula: C6H10 Molecular Weight: 82.15 Purity/Analysis Method: >96.0% (GC) Form: Clear Liquid Boiling point (°C): 38 Flash Point (°C): -34 Specific Gravity (20/20): 0.67 Storage Temperature: 0-10°C
Supplier:
TCI America
Description:
Ethyl 6-Methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate, Purity: >98.0%(HPLC)(N), CAS Number: 5395-36-8, MF: C14H16N2O3, Synonym: 6-Methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylic Acid Ethyl Ester, Form: Crystal - Powder, Solid, White, Size: 1G
Catalog Number:
(PI21340)
Supplier:
Invitrogen
Description:
Thermo Scientific EZ-Link Hydrazide-LC-Biotin is a mid-length, simple, hydrazide-activated biotinylation reagent for labeling glycoproteins and other carbohydrate-containing compounds having oxidizable sugars or aldehydes.
Supplier:
Adipogen
Description:
Diacylglycerol acyltransferase (DGAT) inhibitor. Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Catalog Number:
(10481-936)
Supplier:
Bioss
Description:
Cell cycle progression is subject to arrest at G1 and G2 checkpoints in response to DNA damage, presumably to allow time for DNA repair prior to entry into S and M phase, respectively. The p53 tumor suppressor is required for one such G1 checkpoint and functions to upregulate expression of GADD 45 and the mitotic inhibitory protein p21. GADD 45 stimulates DNA excision repair in vitro and inhibits entry of cells into S phase, and it apparently acts in concert with GADD 153 in inducing growth arrest. A related DNA-damage inducible gene, GADD 34 synergizes with GADD 45 or GADD 153 in suppressing cell growth. PEG-3 (progression elevated gene-3) shares significant homology with GADD 34 and is inducible by DNA damage. An additional GADD related gene, PA26, is a possible target of p53. Three isoforms of PA26 have been identified as PA26-T1, PA26-T2 and PA26-T3.
Catalog Number:
(10481-940)
Supplier:
Bioss
Description:
Cell cycle progression is subject to arrest at G1 and G2 checkpoints in response to DNA damage, presumably to allow time for DNA repair prior to entry into S and M phase, respectively. The p53 tumor suppressor is required for one such G1 checkpoint and functions to upregulate expression of GADD 45 and the mitotic inhibitory protein p21. GADD 45 stimulates DNA excision repair in vitro and inhibits entry of cells into S phase, and it apparently acts in concert with GADD 153 in inducing growth arrest. A related DNA-damage inducible gene, GADD 34 synergizes with GADD 45 or GADD 153 in suppressing cell growth. PEG-3 (progression elevated gene-3) shares significant homology with GADD 34 and is inducible by DNA damage. An additional GADD related gene, PA26, is a possible target of p53. Three isoforms of PA26 have been identified as PA26-T1, PA26-T2 and PA26-T3.
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