DIAGNOSTIC BIOSYSTEMS INC
Supplier:
Diagnostic Biosystems
Description:
This antibody is specific for α-skeletal muscle actinin and α-cardiac actinin. It stains Z lines and dots in stress fibers of myotubes in skeletal and cardiac muscle but not in non-sarcomeric muscle elements.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with the zymogen as well as the activated form of cathepsin D. It stains fibroblasts and macrophages strongly but stains weakly with the myoepithelial cells of breast. It stains the sweat ducts and glands in the skin, islets cells and granules of pancreatic acini.
Catalog Number:
(76634-624)
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with the heavy chain present in all types of human IgM. It stains B cell follicles in human lymphoid tissues. In lymphoid tissues, IgM containing plasma cells stain strongly but immune complexes are usually undetectable.
Catalog Number:
(76634-532)
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with the 54 kDa (flagellin) of <i>H. pylori</i>. The antibody stains the bacteria present on the surface of the epithelium or in the cytoplasm of the epithelial cells.<i> H. pylori</i> is known to cause peptic ulcer and chronic gastritis in humans.
Catalog Number:
(76634-346)
Supplier:
Diagnostic Biosystems
Description:
This antibody recognizes keratin polypeptide of 54 kDa. It stains a number of epithelial cells including ductal and glandular epithelia. Stratified squamous epithelia are positive but transitional epithelium of the urinary tract does not show any staining. This antibody labels adenocarcinomas and transitional carcinomas but does not react with squamous cell carcinomas.
Supplier:
Diagnostic Biosystems
Description:
This antibody recognizes human retinoblastoma gene protein. Rb gene, a prototype of tumor suppressor genes, has been associated with development and/or progression of bladder cancer as well as sarcoma and small cell lung cancer. Functional Rb gene loss has been reported to occur in bladder cancer and osteosarcoma. A significantly poorer tumor-free survival rate was noted for those patients who had a tumor with an altered Rb protein with or without vascular invasion.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with two glycoproteins of 34 and 49 kDa present on the epithelial cells. It stains with simple epithelia and basal layers of stratified non-keratinized squamous epithelium.
Catalog Number:
(99990-832)
Supplier:
Diagnostic Biosystems
Description:
Clone number 2B11+PD7/26, The human leukocyte common antigen is a family of five or more high molecular weight glycoproteins of MW 180, 190, 205 and 220 kD, present on the surface of the majority of human leucocytes. This antibody labels lymphoid cells. .
Catalog Number:
(76634-560)
Supplier:
Diagnostic Biosystems
Description:
P16 is a mitotic inhibitor protein. It competes with D-type cyclins to bind to cdk4 and cdk6. It acts as tumor suppressor and inhibits the progression of cells through the G1 phase of the cell cycle.
Catalog Number:
(76634-452)
Supplier:
Diagnostic Biosystems
Description:
Wilms tumor-1 (WT-1), is a gene involved in the induction of Wilms tumor, a pediatric renal malignancy. Wilms tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilms tumor and mesothelioma.
Supplier:
Diagnostic Biosystems
Description:
This antibody is specific to two proteins of 185 kDa and 145 kDa, identified as two isoforms of neural cell adhesion molecules (NCAM/CD56). NCAM is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytoma and neuroblastoma.
Catalog Number:
(10065-156)
Supplier:
Diagnostic Biosystems
Description:
The Mouse UnoVue HRP/DAB Detection System is a polymer-based 1-step horseradish peroxidase-labeled detection system for immunohistochemistry. This kit can detect mouse IgG and IgM antibodies, with significantly lower background than biotin/avidin detection systems.
Supplier:
Diagnostic Biosystems
Description:
This antibody recognizes Chromogranin A. Chromogranin A (a protein of 439 amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts specifically with CA 125 ovarian cancer antigen
Catalog Number:
(10065-178)
Supplier:
Diagnostic Biosystems
Description:
The Papanicolaou (PAP) Stain Kit is designed to differentiate between a variety of cells in vaginal smears for detection of vaginal, uterine and cervical cancer.
Supplier:
Diagnostic Biosystems
Description:
PermaGreen Plus/AP is a substrate-chromogen system designed for either IHC or ISH when utilizing alkaline phosphatase
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