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Van Der Voort Lucht en Milieu Amste
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Van Der Voort Lucht en Milieu Amste
Supplier:
Adipogen
Description:
Mycotoxin. Protein farnesyltransferase (PFTase) inhibitor. Anti-cancer compound. Directly interacts with P-glycoprotein and inhibits the efflux of antitumor agents in drug resistant cells.
Catalog Number:
(102513-228)
Supplier:
Adipogen
Description:
Human CD137L (4-1BB ligand) is a type II transmembrane protein constitutively expressed by monocytes, B cells and neuroblastoma cells. Binding of CD137 (4-1BB) to CD137L induces monocyte activation.
Catalog Number:
(102513-692)
Supplier:
Adipogen
Description:
Naphthomycin B is an ansamycin antibiotic.
Catalog Number:
(102512-050)
Supplier:
Adipogen
Description:
Human CD14 is strongly expressed on myelomonocyte lineage cells including monocytes, macrophages and a subset of granulocytes. CD14 is a high affinity receptor for complexes of lipopolysaccharide and lipopolysaccharide binding protein. A soluble form of CD14 also binds to LPS and LBP.
Catalog Number:
(102512-138)
Supplier:
Adipogen
Description:
Human CD23 is a low affinity receptor for IgE (Fc epsilon RII) found primarily on mature B cells and also on eosinophils, monocytes, dendritic cells, platelets and a subset of thymic epithelial cells. CD23 interacts with CD21.
Supplier:
Adipogen
Description:
Major naproxen demethylation metabolite. Naproxen demethylation is mediated primarily by CYP2C9. Can be used for assaying naproxen metabolites.
Supplier:
Adipogen
Description:
Potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3alpha/beta, CK2 and PIM1. Interacts with the complex PIKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against APP-induced cell death. Tools to study and modulate pre-RNA splicing. Potential compound for Alzheimer's disease and diseases involving abnormal pre-mRNA splicing. Potential compound to study Down syndrome (inhibition of DYRK1A). Neuroprotective against glutamate-induced cell death. Autophagy activator.
Supplier:
Adipogen
Description:
ANGPTL3 (Angiopoietin-like protein 3) regulates angiogenesis and also directly regulates lipid, glucose, and energy metabolism.
Catalog Number:
(102512-146)
Supplier:
Adipogen
Description:
Human CD24 is a glycosyl phosphatidyl inositol (GPI) anchored surface protein found on B cells during multiple stages of development from precursor to the onset of plasma cell differentiation. Expression of CD24 has been observed to be a lineage predictor in AML.
Supplier:
Adipogen
Description:
Cell permeable spin trap commonly used in free radical research for both in vivo and in vitro studies. It protects against oxidative damage caused by various inflammatory events, demonstrating neuroprotective, anti-anging, and antidiabetic effects. PBN has been shown to inhibit LPS-induced NF-kappaB DNA binding activity, inhibit COX-2 catalytic activity, inhibit lipid peroxidation in rat liver microsomes and prevent the induction of inducible nitric oxide synthase (iNOS). Shows anti-cancer activity in several experimental cancer models.
Catalog Number:
(102513-180)
Supplier:
Adipogen
Description:
TNF (Tumor necrosis factor; cachexin; cachectin and formerly known as tumor necrosis factor-alpha) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction.
Catalog Number:
(102513-322)
Supplier:
Adipogen
Description:
Human DR3 (TRAMP; LARD) was designated TNF receptor superfamily member 25. TL1A is a ligand which can induce apoptosis through a cytoplasmic death domain similar to the CD178-CD95 (FasL-Fas) interaction. Alternatively, engagement of DR3 on T cells can synergize with other activating signals to enhance IFNgamma production.
Supplier:
Adipogen
Description:
Antibiotic. Antiprotozoal. Antimicrobial. Cytotoxic and genotoxic in various mammalian cells. Mitochondrial permeability transition pore (MPTP) activator. Apoptosis inducer. ERK and JNK signaling pathways activator. Nephrotoxic mycotoxin. Suppresses NO and iNOS expression via inhibition of the JAK/STAT-1alpha and NF-kappaB signaling pathways. Tubulin polymerization and mitotic spindle assembly inhibitor. Increases reactive oxygen species (ROS). Induces cell cycle arrest at the G0/G1 and G2/M phase.
Catalog Number:
(102981-496)
Supplier:
Adipogen
Description:
CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. CD160-Fc fusion protein targets a novel costimulatory pathway and prolongs allograft survival.
Catalog Number:
(102511-854)
Supplier:
Adipogen
Description:
Human CD2 is a T-lineage glycoprotein with roles in cell-cell adhesion and the transduction of activation signals. Multiple ligands for CD2 include CD58 (LFA-3), CD59, and CD48. CD2 may play a role in regulating T cell anergy.
Supplier:
Adipogen
Description:
Anhydrotetracycline hydrochloride is a tetracycline derivative.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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