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IKK-2


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Supplier:  ANTIBODIES.COM LLC
Description:   Rabbit polyclonal antibody to IKK alpha (phospho Ser176) + IKK beta (phospho Ser177) for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.
Catalog Number: (10049-382)

Supplier:  Enzo Life Sciences
Description:   Nuclear factor κ B (NF-κB) is a ubiquitous and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-κB is associated with IkappaB proteins in the cell cytoplasm, which inhibit NF-κB activity. IkappaB is phosphorylated by IkappaB kinase (IKK) complex that contains IKKalpha, IKKbeta, and IKKgamma. A molecule in the IKK complex was identified and designated IKKepsilon/IKK-iota.
Catalog Number: (10162-882)

Supplier:  Genetex
Description:   Rabbit Polyclonal antibody to IKK-alpha/beta

Supplier:  Novus Biologicals
Description:   The IKK gamma Antibody (72C627) from Novus Biologicals is a mouse monoclonal antibody to IKK gamma. This antibody reacts with human, mouse. The IKK gamma Antibody (72C627) has been validated for the following applications: Western Blot, Simple Western.
Supplier:  ANTIBODIES.COM LLC
Description:   Rabbit monoclonal [ARC2632] antibody to IKK beta for ICC/IF with samples derived from Mouse and Rat.
Catalog Number: (89278-992)

Supplier:  Genetex
Description:   Rabbit polyclonal to IKK alpha
Catalog Number: (89279-124)

Supplier:  Genetex
Description:   Rabbit polyclonal to IKK gamma
Supplier:  Novus Biologicals
Description:   The IKK gamma Antibody (46B844) [Allophycocyanin] from Novus Biologicals is a mouse monoclonal antibody to IKK gamma. This antibody reacts with human. The IKK gamma Antibody (46B844) [Allophycocyanin] has been validated for the following applications: Flow Cytometry.

Supplier:  Bioss
Description:   IKK beta (I-Kappa-B kinase-beta) is a member of the IKK complex which is composed of IKK alpha, IKK beta, IKK gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1. Once activated, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK beta activity can also be regulated by MEKK1.
Supplier:  Abnova
Description:   Rabbit polyclonal antibody raised against synthetic phosphopeptide of IKK-alpha/beta.
Catalog Number: (75934-642)

Supplier:  Rockland Immunochemical
Description:   IKK gamma control protein-GST fusion

Supplier:  Bioss
Description:   IKK beta (I-Kappa-B kinase-beta) is a member of the IKK complex which is composed of IKK alpha, IKK beta, IKK gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1. Once activated, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK beta activity can also be regulated by MEKK1.

Supplier:  Bioss
Description:   IKK beta (I-Kappa-B kinase-beta) is a member of the IKK complex which is composed of IKK alpha, IKK beta, IKK gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1. Once activated, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK beta activity can also be regulated by MEKK1.

Supplier:  ABCAM INC.
Description:   Anti-IKK alpha Mouse Monoclonal Antibody [clone: ABM10G9]
New Product
Catalog Number: (89415-508)

Supplier:  Prosci
Description:   CIKS Antibody: Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa B mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kappa B associates with I kappa B proteins in the cell cytoplasm, which inhibit NF-kappa B activity. I kappa B is phosphorylated by I kappa B kinase (IKK) complex that contains IKK alpha , IKK beta , and IKK gamma. A novel molecule that associates with and activates IKK was recently identified and designated CIKS (for connection to IKK and SAPK/JNK) and Act1 (for NF-kappa B activator 1). CIKS directly interacts with IKK gamma. CIKS/Act1 also activates activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (JNK). These results indicate that CIKS/Act1 is involved in the inflammation and stress responses. CIKS/Act1 is ubiquitously expressed in human tissues.

Supplier:  ANTIBODIES.COM LLC
Description:   Rabbit polyclonal antibody to IKK-gamma (phospho Ser31) for WB, IHC and ELISA with samples derived from Human.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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