OPTEM
Catalog Number:
(103259-968)
Supplier:
Southern Biotechnology
Description:
The monoclonal antibody DX5 reacts with CD49b, also known as very late antigen-2 (VLA-2) and α2 integrin. The antibody stains the majority of NK cells and a small subpopulation of T cells in all mouse strains tested (e.g., A/J, AKR, BALB/c, C3H/HeJ, C57BL/6, C57BL/10, C57BR, C58, CBA/Ca, CBA/J, DBA/1, DBA/2, SJL, SWR). Three-color flow cytometry analysis has revealed that most cells that express NK-1.1 (NKR-P1C) also express CD49b. However, small subsets of DX5+NK-1.1- and DX5-NK-1.1+ cells can be found, especially among the CD3+ population of T lymphocytes. NK cells cultured in the presence of IL-2 progressively lose reactivity with DX5 as a consequence of cellular proliferation. Therefore, DX5 can be used to define functionally distinct subsets of murine NK cells. The monoclonal antibody DX5 has not been demonstrated to have activating or blocking activity.
Catalog Number:
(103260-034)
Supplier:
Southern Biotechnology
Description:
Purified Goat Anti-Bovine Serum Albumin antibody with minimal reactivity human serum albumin for use in ELISA assays.
Catalog Number:
(103259-986)
Supplier:
Southern Biotechnology
Description:
Goat Anti-Human IgG-Alexa Fluor 555 antibody with minimal reactivity to rhesus and cynomolgus proteins for use in fluorescent assays.
Catalog Number:
(103260-002)
Supplier:
Southern Biotechnology
Description:
Goat Anti-Human Kappa-AP antibody with minimal reactivity to mouse proteins for use in ELISA assays.
Catalog Number:
(103264-464)
Supplier:
Southern Biotechnology
Description:
Goat Anti-Mouse IgG3-HRP antibody with minimal reactivity to human, bovine, and horse serum proteins for use in ELISA assays.
Catalog Number:
(103260-146)
Supplier:
Southern Biotechnology
Description:
In the chicken, the CD8 molecule is present in two forms - (i) a homodimer of two α chains and (ii) a heterodimer of an α chain and a β chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8α- and CD8β-chains, a relatively large proportion of the CD8+ TCRγδ cells in the spleens of embryos and young chicks express only the α-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCRγδ CD8αβ cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80% of thymocytes, 15% of blood mononuclear cells, and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow. The monoclonal antibody CT-8 recognizes the CD8α chain and has been shown to react to a polymorphic determinant in turkey.
Catalog Number:
(103260-132)
Supplier:
Southern Biotechnology
Description:
CD3 is a member of the T cell receptor-associated CD3 complex. The monoclonal antibody CT-3 recognizes a complex of at least three polypeptides of Mr 20, 19, and 17 kDa (two of which are N-glycosylated) on chicken T cells. The antibody also coprecipitates a polypeptide of 90 kDa from digitonin solubilized T cell lysates, which can be reduced to two polypeptides of Mr 50 and 40 kDa.
Catalog Number:
(103260-076)
Supplier:
Southern Biotechnology
Description:
The monoclonal antibody 74-22-15 reacts with > 90% of porcine monocytes and granulocytes and < 5% of peripheral blood lymphocytes.
Catalog Number:
(103260-204)
Supplier:
Southern Biotechnology
Description:
CD5, a member of the scavenger receptor superfamily of cell surface receptors, is a type I transmembrane glycoprotein whose ligand is CD72. It is expressed on most thymocytes, all mature T cells, and a subset of B cells. CD5 plays a role in regulation of T cell activation and signaling.
Catalog Number:
(103260-112)
Supplier:
Southern Biotechnology
Description:
Purified Swine Anti-Rabbit IgG(H+L) antibody with minimal reactivity to human, mouse, rat, and goat serum proteins for use in ELISA assays.
Catalog Number:
(103264-576)
Supplier:
Southern Biotechnology
Description:
CD45 is the common leukocyte antigen and is expressed on all cells of hematopoietic origin except erythrocytes. CD45 exists as a number of different isoforms which result from alternative RNA splicing of exons 4, 5 and 6. The I3/2.3 monoclonal antibody recognizes a framework epitope present on all CD45 isoforms. The CD45 molecule has been implicated as playing a key role in thymic development and in antigen-driven proliferation of T cells.
Catalog Number:
(103265-682)
Supplier:
Southern Biotechnology
Description:
Chicken CD44 is a type I transmembrane glycoprotein expressed on many cell types including B cells, most T cells, monocytes, and some epithelial cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis, and development. The monoclonal antibody AV6 also reacts with turkey peripheral blood mononuclear cells.
Catalog Number:
(103265-692)
Supplier:
Southern Biotechnology
Description:
CD11a, also known as leukocyte function-associated antigen-1 (LFA-1α), represents the 180 kDa integrin αL subunit which combines with the CD18 β2 integrin subunit to form the αLβ2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.
Catalog Number:
(103264-762)
Supplier:
Southern Biotechnology
Description:
Goat F(ab')2 Anti-Human IgD-Alexa Fluor 488 antibody for use in flow cytometry and immunohistochemistry assays.
Catalog Number:
(103264-754)
Supplier:
Southern Biotechnology
Description:
Goat Anti-Human IgM-FITC antibody with minimal reactivity to mouse, bovine, and horse serum proteins for use in fluorescent assays.
Catalog Number:
(103259-812)
Supplier:
Southern Biotechnology
Description:
Goat Anti-Mouse IgG2b-HRP antibody for use in ELISA assays.
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This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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