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(R)-3-Methoxypiperidine+hydrochloride
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(R)-3-Methoxypiperidine+hydrochloride
Supplier:
Adipogen
Description:
CC-401 is a competitive inhibitor of the ATP binding site in the active, phosphorylated, form of JNK. This prevents JNK from phosphorylating its various target molecules, including the amino terminus of c-Jun. It is a potent inhibitor of all three forms of JNK (Ki of 25-50 nM), and has at least 40-fold selectivity for JNK compared with other related kinases, including: p38, ERK, IKK2, PKC, Lck, and ZAP70. CC-401 acts to inhibit JNK signaling by competitive binding to the adenosine triphosphate-binding site in the active, phosphorylated, form of JNK, resulting in inhibition of the phosphorylation of JNK targets, such as the amino-terminal activation domain of the transcription factor, c-Jun. In cell-based assays, 1-5 muM CC-401 provides specific JNK inhibition.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 053769-2.5G , MDL Number: MFCD09055083
Supplier:
Enzo Life Sciences
Description:
Potent and selective AMPK inhibitor.
Supplier:
ALADDIN SCIENTIFIC
Description:
ADL5859 is a δ-opioid receptor agonist with Ki of 0.8 nM, selectivity against opioid receptor κ, μ, and weak inhibitory activity at the hERG channel.A selective receptor agonist for the δ-opioid receptor
Supplier:
Matrix Scientific
Description:
MF=C14H18CLNO3 MW=283.76 CAS=3939-01-3 MDL=MFCD00012799 100G
Supplier:
Adipogen
Description:
AT7519 is a potent inhibitor of several CDK family members. AT7519 showed potent antiproliferative activity (40-940nM) in a panel of human tumor cell lines, and the mechanism of action was shown here to be consistent with the inhibition of CDK1 and CDK2 in solid tumor cell lines. AT7519 caused cell cycle arrest followed by apoptosis in human tumor cells and inhibited tumor growth in human tumor xenograft models. Tumor regression was observed following twice daily dosing of AT7519 in the HCT116 and HT29 colon cancer xenograft models. Also it has been shown that the biological effects are linked to inhibition of CDKs in vivo and that AT7519 induces tumor cell apoptosis in these xenograft models. Moreover, AT7519 has an attractive biological profile and is well tolerated and effective making it a more plausible candidate for clinical development than previously available CDK inhibitors. In in vitro kinase assays AT7519 showed nanomolar levels of activity from <lt/>10 to 2400 for cyclins; only one other non-cyclin related kinase was inhibited at levels below 10µM (GSK3beta, 89nM), all others tested had IC(50)'s of greater than 10,000nM.
Supplier:
AMBEED, INC
Description:
5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone hydrochloride 95%
Supplier:
AMBEED, INC
Description:
Dimethyl spiro[3.3]heptane-2,6-dicarboxylate, Purity: 95%, CAS Number: 37942-79-3, Appearance: Solid or liquid, Storage: Sealed in dry, 2-8 C, Size: 100mg
Supplier:
VWR International
Description:
Eosin Y 1% Alcoholic is a cytoplasmic stain that when used in the hematoxylin and eosin staining procedure provides excellent definition of cell components in shades of red and pink.
Supplier:
AMBEED, INC
Description:
Spiro[2.3]hexan-5-one ≥98%
Catalog Number:
(76874-508)
Supplier:
AMBEED, INC
Description:
Spiro[2.5]octan-6-ylmethanol 97%
Supplier:
AMBEED, INC
Description:
Spiro[fluorene-9,9'-xanthene], Purity: 97%, CAS Number: 159-62-6, Appearance: Solid, Storage: Sealed in dry, Room Temperature, Size: 1g
Supplier:
AMBEED, INC
Description:
6'-(Ethyl(isopentyl)amino)-3'-methyl-2'-(phenylamino)-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one 97%
Supplier:
Matrix Scientific
Description:
6-[(tert-Butoxycarbonyl)amino]spiro[3.3]heptane-2-carboxylic acid ethyl ester 95
Supplier:
AMBEED, INC
Description:
Spiro[cyclohexane-1,3'-indolin]-2'-one 95%
Supplier:
AMBEED, INC
Description:
Spiro[2.5]octane-6-carboxylic acid 97%
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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