Supplier >
Van Der Voort Lucht en Milieu Amste
Print…
You Searched For:
4,061 results were found
Van Der Voort Lucht en Milieu Amste
Catalog Number:
(102511-884)
Supplier:
Adipogen
Description:
The human CD1 genetic locus consists of five closely related genes. Three of the gene products (CD1a, CD1b and CD1c) have been officially clustered using antibodies and are expressed on cortical thymocytes, a subset of B cells, and on most professional antigen presenting cells. CD1 molecules have a specialized lipid antigen-presenting function and it is unlikely that they present conventional peptide antigens. CD1 may also be involved in costimulation.
Catalog Number:
(102989-014)
Supplier:
Adipogen
Description:
Eremophilane sesquiterpene. Nontoxic secondary metabolite from Penicillium roqueforti.
Catalog Number:
(102987-452)
Supplier:
Adipogen
Description:
Potent, selective and cell-permeable inhibitor of Nedd8 E1 Activating Enzyme (NAE). By inhibiting the Neddylation pathway this molecule disrupts cullin-RING ligase activity, leading to inhibition of proliferation or apoptotic death of various human tumor cells through the deregulation of S-phase DNA synthesis.
Supplier:
Adipogen
Description:
alpha-Glucosidase inhibitor. Antioxidant. HIF-1 alpha inhibitor. Anti-metastatic. Apoptosis inducer. Tumor suppressor. Adipogenesis inhibitor. Inhibits SIRT6 in vitro. Inhibits polyubiquitin synthesis by the ubiquitin-conjugating enzyme E2-25K. Cardioprotective. Anti-inflammatory. Shows analgesic effect by targeting TRPV1 channel activity. Neuroprotective. Inhibits NMDA receptors.
Catalog Number:
(102511-964)
Supplier:
Adipogen
Description:
Human CD8 is a heterodimeric protein consisting of an alpha and beta chain, each about 33kDa. CD8 is expressed on most thymocytes and on about one third of peripheral blood T cells. CD8 is a co-receptor involved in antigen recognition and binds to the alpha2 and alpha3 domain of MHC Class I molecules.
Catalog Number:
(102512-848)
Supplier:
Adipogen
Description:
CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development and germinal center formation. The interaction of CD40-CD40L is necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages. Consistent with its widespread expression on normal cells, CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.
Catalog Number:
(102513-370)
Supplier:
Adipogen
Description:
The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology), and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE.
Catalog Number:
(102512-078)
Supplier:
Adipogen
Description:
Antibodies to human CD17 react with lactosylceramide which is expressed on granulocytes, monocytes, platelets and basophils. CD17 expression is downmodulated on activated granulocytes. CD17 is an important component in CD11b/CD18 mediated phagocytosis of microbes.
Catalog Number:
(102514-356)
Supplier:
Adipogen
Description:
Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
Catalog Number:
(102511-442)
Supplier:
Adipogen
Description:
Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
Catalog Number:
(102513-200)
Supplier:
Adipogen
Description:
Human CD252 (CD134L; OX40 ligand) is a type II membrane protein with homology to TNF which is expressed on activated B cells and activated endothelial cells. CD252 binds to CD134 (OX40) present on activated T cells, providing a costimulatory signal. Blockade of this interaction in mouse abrogated immunological effects in several models of inflammation and rejection.
Catalog Number:
(102988-314)
Supplier:
Adipogen
Description:
Mycotoxin
Catalog Number:
(102511-948)
Supplier:
Adipogen
Description:
Human CD7 is one of the earliest T lineage markers and is found on most thymocytes and peripheral blood T cells. The function of CD7 is not yet fully known, although cross-linking of CD7 with antibodies induces a T cell transmembrane calcium flux and CD7 expression is induced by ionomycin.
Supplier:
Adipogen
Description:
Building block for oligonucleotide synthesis.
Catalog Number:
(102512-228)
Supplier:
Adipogen
Description:
Human CD32 exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-transducing capabilities involved with humoral and cell-mediated immune responses.
Supplier:
Adipogen
Description:
Fluorescent reagent with high selectivity.
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
|
|||||||||
List View
