AZD-7762
Supplier:
AMBEED, INC
Description:
AZD-4547 98%
Supplier:
ALADDIN SCIENTIFIC
Description:
AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM, weaker activity against FGFR4, VEGFR2(KDR), and little activity observed against IGFR, CDK2, and p38. Phase 2/3.A novel selective FGFR inhibitor targeting FGFR1, FGFR2, and FGFR3.
Supplier:
ALADDIN SCIENTIFIC
Description:
AZD1981 is a potent, selective CRTh2 (DP2) receptor antagonist with IC50 of 4 nM, showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1.
Supplier:
AMBEED, INC
Description:
AZD-3759 98%
Supplier:
ALADDIN SCIENTIFIC
Description:
AZD8055 is a novel ATP-competitive mTOR inhibitor with IC50 of 0.8 nM with excellent selectivity (~1,000-fold) against PI3K isoforms and ATM/DNA-PK.
Supplier:
Adipogen
Description:
AZD2014 is a dual mTORC1/mTORC2 inhibitor for the treatment of advanced solid malignancies.
Supplier:
ALADDIN SCIENTIFIC
Description:
AZD-8186 ≥98%, Moligand™
Supplier:
AMBEED, INC
Description:
AZD-0156 99%
Supplier:
AMBEED, INC
Description:
AZD-8055 98%
Supplier:
AMBEED, INC
Description:
2-(4-((4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)-N-methylacetamide, Purity: 98%, CAS Number: 848942-61-0, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 100mg
Supplier:
AMBEED, INC
Description:
AZD-4635 97%
Supplier:
ALADDIN SCIENTIFIC
Description:
AZD5363 potently inhibits all isoforms of Akt(Akt1/Akt2/Akt3) with IC50 of 3 nM/8 nM/8 nM in cell-free assays, similar to P70S6K/PKA and lower activity towards ROCK1/2.
Supplier:
ALADDIN SCIENTIFIC
Description:
AZD-5438 ≥98%, Moligand™
Supplier:
AMBEED, INC
Description:
AZD-9291 mesylate 98% (Content MsOH 15.2-18.2%), Ambeed.Inc
Supplier:
Adipogen
Description:
AZD8055 is a novel ATP-competitive inhibitor of mTOR kinase activity with an IC(50) of 0.8nM. It shows excellent selectivity (~1,000-fold) against all class I phosphatidylinositol 3-kinase (PI3K) isoforms and other members of the PI3K-like kinase family.
Supplier:
Adipogen
Description:
AZD-26 is an inhibitor of AKT. AZD-26 inhibits the phosphorylation of Thr308 on AKT in BT474 cells with an IC(50) of 422nM. It also inhibits the phosphorylation of Ser473 on AKT in MDAMB468 cells with an IC(50) of 322nM. AZD-26 inhibited AKT mediated phosphorylation at ranges form 0.01µM to 10µM after 24 hour exposure in several rat and human cell models. Likewise AZD-25 used at 100-200mg/kg also inhibited AKT phosphorylation and subsequent activation.
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