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OPTEM
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OPTEM
Supplier:
Southern Biotechnology
Description:
CD45RC represents an exon C-dependent isoform of CD45 glycoprotein. It is expressed at high density on all B lymphocytes, at intermediate density on most CD8+ splenic T cells, and on two subpopulations of CD4+ splenic T cells with high and low density of expression. CD45RC is also present on a small subset of thymocytes.
Catalog Number:
(100244-298)
Supplier:
Southern Biotechnology
Description:
Goat F(ab')2 Anti-Human IgG-PE antibody for use in flow cytometry assays.
Catalog Number:
(100243-948)
Supplier:
Southern Biotechnology
Description:
CD81, also known as TAPA-1, is an integral membrane protein expressed on a variety of cell types and has a high degree of sequence homology between human and mouse. CD81 is expressed on thymic stromal cells where it plays an important role in the transition of γδ+ T cells to more mature T cells with αβ T cell receptors. Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor which is composed of a TCR β chain and glycoprotein pTα. The monoclonal antibody 2F7 can block thymocyte interaction with CD81 in vitro.
Catalog Number:
(100243-478)
Supplier:
Southern Biotechnology
Description:
CD40 is a type I cell surface protein belonging to the tumor necrosis factor superfamily of cell surface receptors. In mice it is expressed on B lineage cells, follicular dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zone of secondary lymphoid organs. CD40 first becomes detectable on a subset of small pre-B II cells in bone marrow with the levels of CD40 expression increasing thereafter during B cell maturation. Immature B cells (IgM+IgDloB220lo) express intermediate levels of CD40, whereas mature B cells (IgM+IgDhiB220hi) express high levels. CD40 has a central role in B cell growth and differentiation, and signaling through CD40 in combination with IL-4 reportedly induces immunoglobulin isotype switching and secretion of IgE. The agonistic 1C10 antibody closely resembles gp39/CD40 ligand in its ability to stimulate proliferation of small, resting B lymphocytes in the absence of other cofactors.
Catalog Number:
(100244-348)
Supplier:
Southern Biotechnology
Description:
Goat Anti-Human Kappa-Biotin antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, and ELISpot assays.
Catalog Number:
(100245-540)
Supplier:
Southern Biotechnology
Description:
PE Anti-Chicken Lambda antibody for use in flow cytometry assays.
Supplier:
Southern Biotechnology
Description:
CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is expressed by activated T cells, macrophages, dendritic cells, activated platelets, tonsillar epithelium, and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential where they may increase adhesion to extracellular matrix and endothelium.
Catalog Number:
(100245-750)
Supplier:
Southern Biotechnology
Description:
Biotin Anti-Human IgG2 Fd antibody for use in ELISA, flow cytometry, immunohistochemistry, western blotting, and immunoprecipitation assays.
Catalog Number:
(100245-696)
Supplier:
Southern Biotechnology
Description:
AP Anti-Human IgG Fc antibody for use in ELISA, western blotting, and ELISpot assays.
Supplier:
Southern Biotechnology
Description:
CD11c is a 150 kDa adhesion glycoprotein that associates with β2 integrin to form the CD11c/CD18 heterodimer that binds CD54 (ICAM-1) and fibrinogen. It is expressed on NK cells, a subset of B and T cells, granulocytes, monocytes, and macrophages. It functions in cytotoxic T cell killing and in neutrophil and monocyte adhesion to endothelium.
Catalog Number:
(100244-638)
Supplier:
Southern Biotechnology
Description:
Purified Anti-Rat Kappa antibody for use in flow cytometry, ELISA, immunohistochemistry, and western blotting assays.
Catalog Number:
(100245-360)
Supplier:
Southern Biotechnology
Description:
Chicken Native Neutralite Avidin (from Egg White), APC (Allophycocyanin)
Catalog Number:
(100245-038)
Supplier:
Southern Biotechnology
Description:
Goat Anti-Feline IgG(H+L)-HRP antibody for use in ELISA and western blotting assays.
Catalog Number:
(100244-390)
Supplier:
Southern Biotechnology
Description:
Goat F(ab')2 Anti-Human Lambda-HRP antibody for use in ELISA and western blotting assays.
Catalog Number:
(100244-594)
Supplier:
Southern Biotechnology
Description:
Purified Anti-Rat IgG2a antibody for use in flow cytometry, ELISA, immunohistochemistry, and ELISpot assays.
Catalog Number:
(100242-272)
Supplier:
Southern Biotechnology
Description:
Goat Anti-Mouse Ig-HRP antibody with minimal reactivity to human proteins for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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